VATER/VACTERL association: Clinical variability and expanding phenotype including laryngeal stenosis
Corresponding Author
Dott. Giovanni Corsello
Cattedra di Patologia Neonatale IMI, Palermo, Italy
Cattedra di Patologia Neonatale, Istituto Materno-Infantile, Università di Palermo, Via Cardinale Rampolla, 1, 90142 Palermo, ItalySearch for more papers by this authorEmiliano Maresi
Istituto di Anatomia Patologica, Università di Palermo, Palermo, Italy
Search for more papers by this authorAnna Maria Corrao
Divisione di Chirurgia Pediatrica, Ospedale dei Bambini “G Di Cristina”, Palermo, Italy
Search for more papers by this authorUbaldo Dimita
Divisione di Neonatologia, Ospedale Buccheri La Ferla, Palermo, Italy
Search for more papers by this authorManlio Lo Cascio
Divisione di Chirurgia Pediatrica, Ospedale dei Bambini “G Di Cristina”, Palermo, Italy
Search for more papers by this authorMarina Cammarata
Cattedra di Patologia Neonatale IMI, Palermo, Italy
Search for more papers by this authorLiborio Giuffrè
Cattedra di Patologia Neonatale IMI, Palermo, Italy
Search for more papers by this authorCorresponding Author
Dott. Giovanni Corsello
Cattedra di Patologia Neonatale IMI, Palermo, Italy
Cattedra di Patologia Neonatale, Istituto Materno-Infantile, Università di Palermo, Via Cardinale Rampolla, 1, 90142 Palermo, ItalySearch for more papers by this authorEmiliano Maresi
Istituto di Anatomia Patologica, Università di Palermo, Palermo, Italy
Search for more papers by this authorAnna Maria Corrao
Divisione di Chirurgia Pediatrica, Ospedale dei Bambini “G Di Cristina”, Palermo, Italy
Search for more papers by this authorUbaldo Dimita
Divisione di Neonatologia, Ospedale Buccheri La Ferla, Palermo, Italy
Search for more papers by this authorManlio Lo Cascio
Divisione di Chirurgia Pediatrica, Ospedale dei Bambini “G Di Cristina”, Palermo, Italy
Search for more papers by this authorMarina Cammarata
Cattedra di Patologia Neonatale IMI, Palermo, Italy
Search for more papers by this authorLiborio Giuffrè
Cattedra di Patologia Neonatale IMI, Palermo, Italy
Search for more papers by this authorAbstract
Vertebral abnormalities and anorectal and tracheoesophageal defects are the main manifestations in the VATER/VACTERL association. Radial defects vary from radial aplasia to thumb duplication. Heart and renal defects are reported with lower frequency. Additional malformations, such as the laryngeal stenosis described in the present patient, may expand the phenotype of the association. The wide spectrum of congenital abnormalities confirms the high clinical variability of VATER/VACTERL association which seems to be due to a disruption of blastogenesis. © 1992 Wiley-Liss, Inc.
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