Glycobiology of Helicobacter pylori and Gastric Disease
Karl-Anders Karlsson
Search for more papers by this authorKarl-Anders Karlsson
Search for more papers by this authorProf. Dr. Beat Ernst
Institut für Molekulare Pharmazie, Universität Basel, Klingenbergstrasse 50, 4051 Basel, Switzerland
Search for more papers by this authorProf. Dr. Gerald W. Hart
Dept. of Biological Chemistry, Johns Hopkins University School of Medicine, 725 N. Wolf St. Rm., 401 Hunterian Baltimore, MD 21205-2185, USA
Search for more papers by this authorProf. Dr. Pierre Sinaý
Dept. de Chimie, URA 1686, Ecole Normale Supérieure, 24 rue Lhomond, 75231 Paris Cedex 05, France
Search for more papers by this authorProf. Dr. Beat Ernst
Institut für Molekulare Pharmazie, Universität Basel, Klingenbergstrasse 50, 4051 Basel, Switzerland
Search for more papers by this authorProf. Dr. Gerald W. Hart
Dept. of Biological Chemistry, Johns Hopkins University School of Medicine, 725 N. Wolf St. Rm., 401 Hunterian Baltimore, MD 21205-2185, USA
Search for more papers by this authorProf. Dr. Pierre Sinaý
Dept. de Chimie, URA 1686, Ecole Normale Supérieure, 24 rue Lhomond, 75231 Paris Cedex 05, France
Search for more papers by this authorSummary
The prelims comprise:
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Introduction
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The Bacterial Surface and Molecular Mimicry
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Host Surfaces and H. pylori Recognition of Glycoconjugates: Unique Complexity
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The Meaning of Multiple Binding Specificities
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Aspects for the Future
References
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B. J. Marshall,
J.R. Warren,
Unidentified curved bacilli in the stomach of patients with gastrititis and peptic ulceration,
Lancet,
1984,
i,
1311–1315.
10.1016/S0140-6736(84)91816-6 Google Scholar
- B.E. Dunn, H. Cohen, M.J. Blaser, Helicobacter pylori, Clin. Microbiol. Rev., 1997, 10, 720–741.
- J.L. Telford, A. Covacci, R. Rappuoli, P. Ghiara, Immunobiology of Helicobacter pylori infection, Curr. Opin. Immunol., 1997, 9, 498–503.
- K.-A. Karlsson, Meaning and therapeutic potential of microbial recognition of host glycoconjugates, Mol. Microbiol., 1998, 29, 1–11.
- R. Bell, G. TorrigianiM, (editors), Towards better carbohydrate vaccines, 1987, John Wiley & Sons, London.
- G.O. Aspinall, M.A. Monteiro, H. Pang, E.J. Walsh, A.P. Moran, Lipopolysaccharides of the Helicobacter pylori type strain TCTC 11637 (ATCC 43504): structure of the O antigen chain and core oligosacchaiide regions, Biochemistry, 1996, 35, 2489–2497.
- G.O. Aspinall, M.A. Monteiro, Lipopolysaccharides of Helicobacter pylori strains P466 and MO19: structures of the O antigen and core oligosaccharide regions, Biochemistry, 1996, 35, 2498–2504.
- G.O. Aspinall, M.A. Monteiro, R.T. Shaver, L.A. Kurjanczyk, J.L. Penner, Lipopolysaccharides of Helicobacter pylori serogroups O:3 and O:6-structures of a class of lipopolysaccharides with reference to the location of oligomeric units of D-glycero-alpha-D-manno-heptose residues, Eur. J. Biochem., 1997, 248, 592–601.
- M.A. Monteiro, K.H. Chan, D.A. Rasko, D.E. Taylor, P.Y. Zheng, B.J. Appelmelk, et al., Simultaneous expression of type 1 and type 2 Lewis blood group antigens by Helicobacter pylori lipopolysaccharides. Molecular mimicry between H. pylori lipopolysaccharides and human gastric epithelial cell surface glycoforms, J. Biol. Chem., 1998, 273, 11533–11543.
- H.P. Wirth, M. Yang, R.M. Peek, K.T. Tham, M.J. Blaser, Helicobacter pylori Lewis expression is related to host Lewis phenotype, Gastroenterology, 1997, 113, 1091–1098.
- A.P. Moran, G.O. Aspinall, Unique structural and biological features of Helicobacter pylori lipopolysaccharides, Prog. Clin. Biol. Res., 1998, 397, 37–49.
- G. Faller, H. Steininger, B. Appelmelk, T. Kirchner, Evidence of novel pathogenic pathways for the formation of antigastric autoantibodies in Helicobacter pylori gastritis, J. Clin. Pathol., 1998, 51, 244–245.
- D.G. Evans, D.J. Evans Jr, J.J. Molds, D.Y. Graham, N-acetylneuraminyllactose-binding fibrillar hemagglutinin of Campylobacter pylori: a putative colonization factor antigen. Infect. Immun., 1988, 56, 2896–2906.
- H. Miller-Podraza, M. Abul Milh, J. Bergström, K.-A. Karlsson, Recognition of glycoconjugates by Helicobacter pylori: An apparently high-affinity binding of human poly-glycosylceramides, a second sialic acid-based specificity, Glycoconj. J., 1996, 13, 453–460.
- T. Saitoh, H. Natomi, W. Zhao, K. Okuzumi, K. Sugano, M. Iwamori, et al., Identification of glycolipid receptors for Helicobacter pylori by TLC immunostaining, FEBS Lett., 1991, 282, 385–387.
- F. Ascencio, L.-Å. Fransson, T. Wadström, Affinity of the gastric pathogen Helicobacter pylori for the N-sulphated glycosaminoglycan heparan sulphate, J. Med. Microbiol., 1993, 38, 240–244.
- T. Borén, P. Falk, K.A. Roth, G. Larson, S. Normark, Atachment of Helicobacter pylori to human gastric epithelium mediated by blood group antigens, Science, 1993, 262, 1892–1895.
- B. Gold, M. Huesca, P. Sherman, C.A. Lingwood, Helicobacter mustelae and Helicobacter pylori bind to common receptors in vitro, Infect. Immun., 1993, 61, 2632–2638.
- J. Ångström, S. Teneberg, M. Abul Milh, T. Larsson, I. Leonardsson, B.-M. Olsson, et al., The lactosylceramide binding specificity of Helicobacter pylori, Glycobiology, 1998, 8, 297–309.
- S. Teneberg, H. Miller-Podraza, H.C. Lampert, D.J. Evans Jr, D.G. Evans, D. Danielsson, et al., Carbohydrate binding specificity of the neutrophil-activating protein of Helicobacter pylori, J. Biol. Chem., 1991, 272, 19067–19071.
- C.A. Lingwood, M. Huesca, A. Kuskis, The glycerolipid receptor for Helicobacter pylori (and exoenzyme S) is phosphatidylethanolamine, Infect. Immun., 1992, 60, 2470–2474.
- S. Hirmo, S. Kelm, R. Schauer, B. Nilsson, T. Wadström, Adhesion of Helicobacter pylori strains to α-2,3-linked sialic acids, Glycoconj. J., 1996, 13, 1–7.
- L. Johansson, K.-A. Karlsson, Selective binding by Helicobacter pylori of leucocyte gangliosides with 3-linked sialic acid, as identified by a new approach of linkage analysis, Glycoconj. J., 1998, 15, 713–721.
- H. Miller-Podraza, T. Larsson, J. Nilsson, S. Teneberg, M. Matrosovich, L. Johansson, Epitope dissection of receptor-active gangliosides with affinity for Helicobacter pylori and influenza virus, Acta Biochim. Polon., 1998, 45, 439–449.
- P.M. Simon, P.L. Goode, A. Mobasseri, D. Zopf, Inhibition of Helicobacter pylori binding to gastrointestinal epithelial cells by sialic acid-containing oligosaccharides, Infect. Immun., 1997, 65, 750–757.
- D.G. Evans, T.K. Karjalainen, D.J. Evans Jr, D.Y. Graham, C.H. Lee, Cloning, nucleotide sequence, and expression of a gene encoding an adhesin subunit protein of Helicobacter pylori, J. Bacteriol., 1993, 175, 674–683.
- P.W. O Toole, L. Janzon, P. Doig, J. Huang, M. Kostrzynska, T.J. Trust, The putative neuraminyllactose-binding hemagglutinin HpaA of Helicobacter pylori CCUG 17874 is a lipoprotein, J. Bacteriol., 1995, 177, 6049–6057.
- A.C. Jones, R.P.H. Logan, S. Foynes, A. Cockayne, B.W. Wren, C.W. Penn, A flagellar sheath protein of Helicobacter pylori is identical to HpaA, a putative N-acetylneuraminyllactose-binding hemagglutinin, but is not an adhesin for AGS cells, J. Bacteriol., 1997, 179, 5643–5647.
- K.H. Valkonen, T. Wadström, A.P. Moran, Identification of the N-acetylneuraminyllactose-specific laminin-binding protein of Helicobacter pylori, Infect. Immun., 1997, 65, 916–923.
- H. Miller-Podraza, J. Bergström, M. Abul Milh, K.-A. Karlsson, Recognition of glycoconjugates by Helicobacter pylori. Comparison of two sialic acid-dependent specificities based on haemagglutination and binding to human erythrocyte glycoconjugates, Glycoconj. J., 1997, 14, 467–471.
- H. Miller-Podraza, G. Stenhagen, T. Larsson, C. Andersson, K.-A. Karlsson, Screening for the presence of polyglycosylceramides in various tissues: Partial characterization of blood group-active complex glycosphingolipids of rabbit and dog small intestines, Glycoconj. J., 1997, 14, 231–239.
- S. Kamisago, M. Iwamori, T. Tai, K. Mitamura, Y. Yazaki, K. Sugano, Role of sulfatides in adhesion of Helicobacter pylori to gastric cancer cells, Infect. Immun., 1996, 64, 624–628.
- M. Huesca, S. Borgia, P. Hoffman, C.A. Lingwood, Acidic pH changes receptor binding specificity of Helicobacter pylori: A binary adhesion model in which surface heat shock (stress) proteins mediate sulfatide recognition in gastric colonization, Infect. Immun., 1996, 64, 2643–2648.
- M. Huesca, A. Goodwin, A. Bhagwansingh, P. Hoffman, C.A. Lingwood, Characterization of an acidic-pH-inducible stress protein (hsp70), a putative sulfatide binding adhesin, from Helicobacter pylori, Infect. Immun., 1998, 66, 4061–4067.
- E.C. Veerman, C.M. Bank, E. Namavar, B.J. Appelmelk, J.G. Bolscher, A.V. Nieuw-Amerongen, Sulfated glycans on oral mucin as receptors for Helicobacter pylori, Glycobiology, 1997, 7, 737–743.
- F. Namayar, M. Sparrius, E.C. Veerman, B.J. Appelmelk, C.M. Vandenbroucke-Grauls, Neutrophil-activating protein mediates adhesion of Helicobacter pylori to sulfated carbohydrates on high-molecular-weight salivary mucins, Infect. Immun., 1998, 66, 444–447.
- M. Utt, T. Wadström, Identification of heparan sulphate binding proteins of Helicobacter pylori: Inhibition of heparan sulfate binding with sulphated carbohydrate polymers, J. Med. Microbiol., 1997, 46, 541–546.
- M. Chmiela, Å. Ljung, W. Rudnicka, T. Wadström, Phagocytosis of Helicobacter pylori bacteria differing in the heparan sulfate binding by human polymorphonuclear leukocytes, Zentralbl. Bakteriol, 1996, 283, 346–350.
- P. Falk, K.A. Roth, T. Borén, U. Westblom, J.I. Gordon, S. Normark, An in vitro adherence assay reveals that Helicobacter pylori exhibits cell lineage-specific tropism in the human gastric epithelium, Proc. Natl Acad. Sci. USA, 1993, 90, 2035–2039.
- D. Ilver, A. Arnqvist, J. Ögren, I.-M. Frick, D. Kersulyte, E.T. Incecik, et al., Helicobacter pylori adhesin binding fucosylated histo-blood group antigens revealed by retagging, Science, 1998, 279, 373–377.
- P.G. Falk, L. Bry, J. Holgersson, J.I. Gordon, Expression of a human α-1,3/4-fucosyltransferase in the pit cell lineage of FVB/N mouse stomach results in production of Leb-containing glycoconjugates: A potential transgenic mouse model for studying Helicobacter pylori infection, Proc. Natl Acad. Sci. USA, 1995, 92, 1515–1519.
- J.L. Guruge, P.G. Falk, R.G. Lorenz, M. Dans, H.-P. Wirth, M.J. Blaser, et al., Epithelial attachment alters the outcome of Helicobacter pylori infection, Proc. Natl Acad. Sci. USA, 1998, 95, 3925–3930.
- K.-A. Karlsson, Animal glycosphingolipids as membrane attachment sites for bacteria, Annu. Rev. Biochem., 1989, 58, 309–350.
- H. Rautelin, B. Blomberg, H. Fredlund, G. Järnerot, D. Danielsson, Incidence of Helicobacter pylori strains activating neutrophils in patients with peptic ulcer disease, Gut, 1993, 34, 599–603.
- D.E. Kirschner, M.J. Blaser, The dynamics of Helicobacter pylori infection in the human stomach, J. Theor. Biol., 1995, 176, 281–290.
- D.J. Evans Jr, D.G. Evans, T. Takemura, H. Nakano, H.C. Lampert, D.Y. Graham, et al., Characterization of a Helicobacter pylori neutrophil-activating protein, Infect. Immun., 1995, 63, 2213–2220.
- J.-F. Tomb, O. White, A.R. Kerlavage, R.A. Clayton, G.G. Sutton, R.D. Fleishmann, et al., The complete genome sequence of the gastric pathogen Helicobacter pylori, Nature, 1997, 388, 539–547.
- R.A. Aim, L.-S.L. Ling, D.T. Moir, B.L. King, E.D. Brown, P.C. Doig, et al., Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori, Nature, 1999, 397, 176–180.
- D. Zopf, S. Roth, Oligosaccharide anti-infective agents, Lancet, 1996, 347, 1017–1021.
- J.C. McAuliffe, O. Hindsgaul, Carbohydrate drugs—an ongoing challenge, Chem. and Ind., 1997, No vol., 170–174.
- S. Teneberg, et al., unpublished results.
- H. Miller-Podraza, S. Teneberg, et al., submitted for publication.
- K.-A. Karlsson, S. Teneberg, et al., unpublished results.