Chapter 67

Lysosomal Degradation of Glycoproteins

Prof. Dr. Beat Ernst

Prof. Dr. Beat Ernst

Institut für Molekulare Pharmazie, Universität Basel, Klingenbergstrasse 50, 4051 Basel, Switzerland

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Prof. Dr. Gerald W. Hart

Prof. Dr. Gerald W. Hart

Dept. of Biological Chemistry, Johns Hopkins University School of Medicine, 725 N. Wolf St. Rm., 401 Hunterian Baltimore, MD 21205-2185, USA

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Prof. Dr. Pierre Sinaý

Prof. Dr. Pierre Sinaý

Dept. de Chimie, URA 1686, Ecole Normale Supérieure, 24 rue Lhomond, 75231 Paris Cedex 05, France

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First published: 27 July 2000

Summary

The prelims comprise:

  • Summary

  • Introduction

  • Roles of Lysosomes

  • Lysosomal Degradation of N-Linked Glycoproteins

  • Formation of Thyroid Hormone via Lysosomal Degradation of Thyroglobulin

  • Degradation of Free Polymannose-Type Oligosaccharides Derived from N-Linked Glycoproteins During Biosynthesis

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