This chapter contains sections titled:

• Introduction

• Pathophysiology

• Causes of upper gastrointestinal hemorrhage

• Morbidity/mortality from upper gastrointestinal bleeding

• History

• Examination and assessment

• Initial management: resuscitation

• Risk assessment

• Investigations

• Medical management of suspected nonvariceal upper gastrointestinal hemorrhage

• Management of variceal upper gastrointestinal hemorrhage

• Summary

• References