Fibroblasts and the Extracellular Matrix

Lynne A. Murray,

Lynne A. Murray

Manager of Pharmacology

Promedior Inc, Malvern, Pennsylvania, USA

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William G. Glass,

William G. Glass

Immunobiology, Centocor, Radnor, Pennsylvania, USA

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Anuk M. Das,

Anuk M. Das

Immunobiology, Centocor, Radnor, Pennsylvania, USA

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Geoffrey J. Laurent,

Geoffrey J. Laurent

Director

Centre for Respiratory Research, Department of Medicine, Rayne Institute, University College London, London, UK

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Lynne A. Murray,

Lynne A. Murray

Manager of Pharmacology

Promedior Inc, Malvern, Pennsylvania, USA

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William G. Glass,

William G. Glass

Immunobiology, Centocor, Radnor, Pennsylvania, USA

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Anuk M. Das,

Anuk M. Das

Immunobiology, Centocor, Radnor, Pennsylvania, USA

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Geoffrey J. Laurent,

Geoffrey J. Laurent

Director

Centre for Respiratory Research, Department of Medicine, Rayne Institute, University College London, London, UK

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Book Editor(s):A. Barry Kay MD, PhD, FRCP, DSc, FRSE, FMedSci,

A. Barry Kay MD, PhD, FRCP, DSc, FRSE, FMedSci

Emeritus Professor of Allergy and Clinical Immunology

National Heart and Lung Institute, Imperial College London, London, UK

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Allen P. Kaplan MD,

Allen P. Kaplan MD

Professor

The National Allergy, Asthma, and Urticaria Centers of Charleston, South Carolina, USA

Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA

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Jean Bousquet MD, PhD,

Jean Bousquet MD, PhD

CHU Montpellier, Service des Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France

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Patrick G. Holt DSc, FRCPath, FAA,

Patrick G. Holt DSc, FRCPath, FAA

Head

Division of Cell Biology, TVW Telethon Institute for Child Health Research, West Perth, Western Australia, Australia

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First published: 25 July 2008

https://doi.org/10.1002/9781444300918.ch18

Summary

This chapter contains sections titled:

Introduction
ECM and the basement membrane
ECM-producing cells
Indirect mediators of fibrosis
Mediators of fibrosis
Clinical targeting of fibrosis in lung pathologies
References

Allergy and Allergic Diseases, Volume 1, Second Edition