Chapter 3

Biochemical Compounds in Phaeodactylum tricornutum

Vandana Sirotiya

Vandana Sirotiya

Diatom Nano Engineering and Metabolism Laboratory (DNM), School of Applied Sciences, Dr. Harisingh Gour Central University Sagar, Madhya Pradesh, India

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Vandana Vinayak

Vandana Vinayak

Diatom Nano Engineering and Metabolism Laboratory (DNM), School of Applied Sciences, Dr. Harisingh Gour Central University Sagar, Madhya Pradesh, India

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First published: 10 March 2025

Summary

A suite of stress factors can trigger the rapid biosynthesis of biochemical compounds like lipid, pigments, carbohydrates, etc., in marine diatom Phaeodactylum tricornutum . Stress factors such as high light intensity, nutrient supplementation, alkaline pH, and nitrogen depletion can potentially affect the natural metabolic processes and induce the accumulation of fucoxanthin and polyunsaturated fatty acids (PUFAs). P. tricornutum has a robust metabolism with the efficiency of an immense array of metabolic fluxes. Characterization of fundamental metabolic pathways, possible regulatory mechanism of central metabolism and enzymes for higher and rapid biosynthesis of biochemical compounds have vital flux roles. Study of these metabolic pathways suggest that these stress factors significantly influence the performance for the biosynthesis and accumulation of a high number of value-added compounds. Demand for natural compounds and their applications in various industries lead to optimization of biosynthesis pathways of biochemical compounds with low-cost stress chemicals as well as other factors for exponential cell growth to obtain a great amount of biomass.

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