Chapter 1

Introduction of 3D Printing and Different Bioprinting Methods

Asmita Biswas

Asmita Biswas

School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India

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Baisakhee Saha

Baisakhee Saha

School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India

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Hema Bora

Hema Bora

School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India

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Pravin Vasudeo Vaidya

Pravin Vasudeo Vaidya

School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India

Advanced Technology Development Centre, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India

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Krishna Dixit

Krishna Dixit

School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India

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Santanu Dhara

Santanu Dhara

School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India

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First published: 05 July 2024

Summary

3D printing is one of the most happening technologies in biomedical research and healthcare sectors. Thanks to this technology, the fabrication of biomedical devices and complicated organs is now possible to extreme limits. The methods of bioprinting in fabrication and tissue engineering involve controlled layer-by-layer deposition by either laser-based method, extrusion printing, droplet printing, inkjet printing, or stereolithography. Complex designs can be manufactured easily with high geometric precision at a low cost in a rapid and environmentally friendly procedure while minimizing material wastage. The bioink used to print engineered or artificial living tissue should have proper mechanical stability, stiffness, printability, viscosity, surface tension, structural integrity, and biological abilities like-biocompatibility and biodegradability. The scope of 3DP ranges from large-scale manufacturing of bone, cartilage, skin, heart, lungs, liver, kidney, urethra, brain, spinal cord, and cornea to therapeutics like cancer, drug, cell, vaccine, and antibiotic deliveries, RNA and drug printing. Finally, this chapter concludes with troubleshooting tips to manage associated complications.

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