Normal haemostasis
Keith Gomez
Haemophilia Centre and Thrombosis Unit, Royal Free London NHS Foundation Trust, London, UK
Search for more papers by this authorJohn H McVey
School of Biosciences and Medicine, University of Surrey, Guildford, UK
Search for more papers by this authorKeith Gomez
Haemophilia Centre and Thrombosis Unit, Royal Free London NHS Foundation Trust, London, UK
Search for more papers by this authorJohn H McVey
School of Biosciences and Medicine, University of Surrey, Guildford, UK
Search for more papers by this authorAdam J Mead PhD, FRCP, FRCPath, FMedSci
Haematopoietic Stem Cell Biology Laboratory, Medical Research Council Molecular Haematology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK
Search for more papers by this authorMichael A Laffan DM, MRCP, FRCPath
Department of Immunology and Inflammation, Faculty of Medicine, Imperial College London, London, UK
Search for more papers by this authorGraham P Collins DPhil, FRCP, FRCPath
Department of Haematology, Oxford Cancer and Haematology Centre, Oxford, UK
Search for more papers by this authorDeborah Hay DPhil, MRCP, FRCPath
Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK
Search for more papers by this authorA Victor Hoffbrand MA, DM, FRCP, FRCPath, FRCP (Edin), DSc, FMedSci
Emeritus Professor of Haematology Honorary Consultant Haematologist
University College London, London, UK
Royal Free Hospital, London, UK
Search for more papers by this authorSummary
This chapter reviews current concepts of haemostasis in humans to provide a background for the haemostatic disorders described in subsequent chapters. It starts with an overview of the response to blood vessel injury. Following this, each of the five main areas are discussed in more detail.
Selected bibliography
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- Aird WC ( 2015 ) Endothelium and haemostasis . Haemostaseologie 35 ( 1 ): 11 – 6 . doi: 10.5482/HAMO-14-11-0075 . PMID: 25666572.
- Grover SP , Mackman N ( 2018 ) Tissue factor: an essential mediator of hemostasis and trigger of thrombosis . Arteriosclerosis, Thrombosis, and Vascular Biology 38 ( 4 ): 709 – 725 . doi: 10.1161/ATVBAHA.117.309846 . Epub 2018 Feb 8. PMID: 29437578.
