Chapter 8

Intravascular Ultrasound

Principles, Image Interpretation, and Clinical Applications

First published: 06 May 2022

Summary

Intravascular ultrasound (IVUS) has become an increasingly important catheter-based imaging technology providing both practical guidance for percutaneous coronary interventions (PCI) as well as many different clinical and research insights. IVUS supplements angiography by providing a tomographic perspective of lumen geometry and vessel wall structure. Artifacts often appear in images generated by contemporary IVUS devices and can interfere in imaging interpretation and measurements. In standard image acquisition after anticoagulation and intracoronary nitroglycerin administration, the IVUS catheter should be placed distal to the segment of interest, and a continuous pullback to the aorta should be recorded. The ultrasound appearance of normal human arteries in vitro and in vivo has been reported. Coronary angiography depicts the coronary anatomy as a longitudinal silhouette of the lumen. PCI optimization with IVUS after stent implantation has been associated with a reduction in death as well as other hard end points of myocardial infarction and stent thrombosis.

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