Medicinal Potentials of Phytochemicals as a Source of Drugs for the Treatment of Onchocerciasis (River Blindness)
Chandrashekar Srinivasa
Department of Biotechnology, Davangere University, Davangere, Karnataka, India
Department of Food Technology, Davangere University, Davangere, Karnataka, India
Search for more papers by this authorChandan Shivamallu
Department of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysore, Karnataka, India
Search for more papers by this authorS. R. Santhosh Kumar
Department of Biotechnology, Davangere University, Davangere, Karnataka, India
Department of Food Technology, Davangere University, Davangere, Karnataka, India
Search for more papers by this authorP. Sushma
Department of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysore, Karnataka, India
Search for more papers by this authorShiva Prasad Kollur
Department of Sciences, Amrita School of Arts and Sciences, Mysore, Karnataka, India
Search for more papers by this authorSeema J. Patel
Department of Biotechnology, Davangere University, Davangere, Karnataka, India
Department of Food Technology, Davangere University, Davangere, Karnataka, India
Search for more papers by this authorS. S. Patil
Virology Laboratory, ICAR – National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Bangalore, Karnataka, India
Search for more papers by this authorR. Suhas
Postgraduate Department of Chemistry, JSS College of Arts, Commerce and Science, Mysore, Karnataka, India
Search for more papers by this authorChukwuebuka Egbuna
Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Uli, Nigeria
Nutritional Biochemistry and Toxicology Unit, World Bank Africa Centre of Excellence, Centre for Public Health and Toxicological Research (PUTOR), University of Port-Harcourt, Port Harcourt, Nigeria
Search for more papers by this authorBui Thanh Tung
VNU School of Medicine and Pharmacy, Vietnam National University, Hanoi, Vietnam
Search for more papers by this authorChandrashekar Srinivasa
Department of Biotechnology, Davangere University, Davangere, Karnataka, India
Department of Food Technology, Davangere University, Davangere, Karnataka, India
Search for more papers by this authorChandan Shivamallu
Department of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysore, Karnataka, India
Search for more papers by this authorS. R. Santhosh Kumar
Department of Biotechnology, Davangere University, Davangere, Karnataka, India
Department of Food Technology, Davangere University, Davangere, Karnataka, India
Search for more papers by this authorP. Sushma
Department of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysore, Karnataka, India
Search for more papers by this authorShiva Prasad Kollur
Department of Sciences, Amrita School of Arts and Sciences, Mysore, Karnataka, India
Search for more papers by this authorSeema J. Patel
Department of Biotechnology, Davangere University, Davangere, Karnataka, India
Department of Food Technology, Davangere University, Davangere, Karnataka, India
Search for more papers by this authorS. S. Patil
Virology Laboratory, ICAR – National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Bangalore, Karnataka, India
Search for more papers by this authorR. Suhas
Postgraduate Department of Chemistry, JSS College of Arts, Commerce and Science, Mysore, Karnataka, India
Search for more papers by this authorChukwuebuka Egbuna
Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Uli, Nigeria
Nutritional Biochemistry and Toxicology Unit, World Bank Africa Centre of Excellence, Centre for Public Health and Toxicological Research (PUTOR), University of Port-Harcourt, Port Harcourt, Nigeria
Search for more papers by this authorBui Thanh Tung
VNU School of Medicine and Pharmacy, Vietnam National University, Hanoi, Vietnam
Search for more papers by this authorChukwuebuka Egbuna
Chukwuemeka Odumegwu Ojukwu University, Uli, Nigeria
Search for more papers by this authorMuhammad Akram
Government College University, Faisalabad, Pakistan
Search for more papers by this authorJonathan Chinenye Ifemeje
Chukwuemeka Odumegwu Ojukwu University, Uli, Nigeria
Search for more papers by this authorSummary
Onchocerciasis is an infection caused by Onchocerca volvulus that causes eye and skin diseases. Infection is transmitted by black flies from one human to another. The infection is widely spread in Africa and more than 99% of the people with this infection live in Africa. The mass drug administration (MDA) campaign has led to the efforts of distributing the ivermectin to eliminate the human onchocerciasis by 2025. In certain regions, the drugs treated against the infection gains resistance to it, thus leading to no cure for the infection. Due to this instance, certain herbal plants which are already in use as traditional medicines for various diseases have been selected and studied for their anti-onchocerca activity.
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