Hematology of Cats
Deanna M. W. Schaefer
Search for more papers by this authorDeanna M. W. Schaefer
Search for more papers by this authorMarjory B. Brooks DVM, DACVIM
Director, Comparative Coagulation Section
Animal Health Diagnostic Center, Cornell University, Ithaca, New York, USA
Search for more papers by this authorKendal E. Harr DVM, MS, DACVP
URIKA, LLC, Mukilteo, Washington, USA
Search for more papers by this authorDavis M. Seelig DVM, PhD, DACVP
Associate Professor, Clinical Pathology
Department of Veterinary Clinical Sciences, University of Minnesota, College of Veterinary Medicine, St. Paul, Minnesota, USA
Search for more papers by this authorK. Jane Wardrop DVM, MS, DACVP
Professor and Director, Clinical Pathology Laboratory
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA
Search for more papers by this authorDouglas J. Weiss DVM, PhD, DACVP
Emeritus Professor
College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, USA
Search for more papers by this authorSummary
Maturation of punctate reticulocytes to mature erythrocytes occurs more slowly in cats than in most other species. The reticulocyte counts produced by automated hematology analyzers typically only include aggregate reticulocytes. The microscopic appearance and cell size of neutrophils, lymphocytes, and monocytes are similar between domestic and nondomestic cats. As in other mammals, feline platelets are small anucleate granular cytoplasmic fragments of megakaryocytes. Blood for hematologic evaluation from cats is commonly collected from a jugular, cephalic, or saphenous vein into a collection tube containing EDTA anticoagulant. Catecholamine-induced leukogram changes are more common in cats than many other domestic species. Cats with endogenous Heinz bodies due to disease typically have low-normal to decreased erythron mass. Numerous bone marrow disorders can be identified in feline leukemia virus (FeLV)-infected cats, including myelodysplasia, leukemia, lymphoma, myelofibrosis, and pure red cell aplasia. Infection with FeLV or feline immunodeficiency virus can be associated with a variety of hematologic abnormalities in cats.
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