Chapter 109

Hematology of Cats

First published: 04 March 2022
Citations: 2

Summary

Maturation of punctate reticulocytes to mature erythrocytes occurs more slowly in cats than in most other species. The reticulocyte counts produced by automated hematology analyzers typically only include aggregate reticulocytes. The microscopic appearance and cell size of neutrophils, lymphocytes, and monocytes are similar between domestic and nondomestic cats. As in other mammals, feline platelets are small anucleate granular cytoplasmic fragments of megakaryocytes. Blood for hematologic evaluation from cats is commonly collected from a jugular, cephalic, or saphenous vein into a collection tube containing EDTA anticoagulant. Catecholamine-induced leukogram changes are more common in cats than many other domestic species. Cats with endogenous Heinz bodies due to disease typically have low-normal to decreased erythron mass. Numerous bone marrow disorders can be identified in feline leukemia virus (FeLV)-infected cats, including myelodysplasia, leukemia, lymphoma, myelofibrosis, and pure red cell aplasia. Infection with FeLV or feline immunodeficiency virus can be associated with a variety of hematologic abnormalities in cats.

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