Chapter 3
Cutaneous Microbiome
Carrie C. Coughlin,
William H. McCoy IV,
Carrie C. Coughlin
Division of Dermatology, Department of Medicine, and Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA
Search for more papers by this authorWilliam H. McCoy IV
Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA
Search for more papers by this authorCarrie C. Coughlin,
William H. McCoy IV,
Carrie C. Coughlin
Division of Dermatology, Department of Medicine, and Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA
Search for more papers by this authorWilliam H. McCoy IV
Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA
Search for more papers by this authorBook Editor(s):Peter Hoeger,
Veronica Kinsler,
Albert Yan,
John Harper,
Arnold Oranje,
Christine Bodemer,
Margarita Larralde,
David Luk, Vibhu Mendiratta,
Diana Purvis,
Peter Hoeger
Search for more papers by this authorVeronica Kinsler
Search for more papers by this authorAlbert Yan
Search for more papers by this authorJohn Harper
Search for more papers by this authorArnold Oranje
Search for more papers by this authorChristine Bodemer
Search for more papers by this authorMargarita Larralde
Search for more papers by this authorVibhu Mendiratta
Search for more papers by this authorDiana Purvis
Search for more papers by this authorFirst published: 20 November 2019
Summary
Bacteria, fungi and viruses comprise the cutaneous microbiome. Exposures starting in utero shape our initial microbiome, which then evolves over time through exposure to external microbial communities (delivery method, close contacts, environment) and changes in our skin's biochemical nature (adrenarche, hygiene, skin disease). This chapter investigates the composition of the microbiome throughout childhood, interactions of the microbiome with the skin barrier and immune system, and microbial contributions to health and disease. Current skin microbiome research related to several common diseases (atopic dermatitis, acne, psoriasis) suggests that incorporation of this information may be beneficial in disease treatment, thus underscoring the need for further studies in this field.
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