Chapter 65

Peritoneal Dialysis in Children

Nathan T. Beins

Nathan T. Beins

Division of Pediatric Nephrology University of Missouri-Kansas City School of Medicine, Children's Mercy Hospital, Kansas City, Missouri, USA

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Bradley A Warady

Bradley A Warady

Division of Pediatric Nephrology University of Missouri-Kansas City School of Medicine, Children's Mercy Hospital, Kansas City, Missouri, USA

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First published: 18 November 2022

Summary

Peritoneal dialysis (PD) is the most popular chronic dialysis modality in children worldwide. Acute kidney injury is a common complication among hospitalized children and in severe cases renal replacement therapy may be instituted. Automated peritoneal dialysis is the predominant PD modality prescribed for children in nonresource limited countries due in part to the social advantages of nocturnal therapy over daytime PD that are characteristic of continuous ambulatory peritoneal dialysis. Peritonitis and catheter-related infections are the primary cause of catheter removal, morbidity, and treatment failure in children who receive chronic PD. Few trials exist examining treatment of peritonitis in the pediatric population. Risk factors and their association with mortality in children on PD are commonly reported, but all studies suffer from the lack of inclusion of children not pursuing renal replacement therapy, transitioning between dialysis modalities, and a short duration of dialysis therapy prior to renal transplantation.

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