Chapter 4

Screening for Chronic Kidney Disease

Mohamed A. Osman

Mohamed A. Osman

Division of Nephrology and Immunology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada

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Kwaifa S. Ibrahim

Kwaifa S. Ibrahim

Department of Medicine, Wuse District General Hospital, Nigeria

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Nikhil Shah

Nikhil Shah

Division of Nephrology and Immunology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada

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Soroush Shojai

Soroush Shojai

Division of Nephrology and Immunology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada

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Ikechi G. Okpechi

Ikechi G. Okpechi

Division of Nephrology and Hypertension, Groote Schuur Hospital, Cape Town, South Africa

Kidney and Hypertension Research Unit, University of Cape Town, Cape Town, South Africa

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Aminu K. Bello

Aminu K. Bello

Division of Nephrology and Immunology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada

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First published: 18 November 2022

Summary

Screening is performed to differentiate healthy people from those in the early stages of disease who are not experiencing symptoms or exhibiting signs of disease who are not experiencing symptoms or exhibiting signs of illness. This chapter discusses the utility of a screening program for chronic kidney disease (CKD) with regard to associated outcomes and costs. CKD treatment plans often are unclear and access to healthcare resources may be limited. CKD diagnosis requires detecting persistent structural or functional abnormalities of the kidney through laboratory measurements. It recommends against screening for CKD in asymptomatic adults without risk factors for CKD. Overall, the effectiveness of CKD screening and treatment could be better measured in a cluster randomized trial that can better capture multiple concurrent effects and their influences on patient outcomes.

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