Chapter 35

Chronic Kidney Disease and Hypertension

Branko Braam

Branko Braam

Division of Nephrology, Department of Medicine, University of Alberta, Canada

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First published: 18 November 2022

Summary

Hypertension is not only highly prevalent in patients with chronic kidney disease (CKD), it is also one of the most prevalent causes of progressive kidney injury and end-stage kidney disease. In the context of clinical evaluation of the patient with CKD, four different assessments of blood pressure (BP) are being used: in-office manual, multiple in-office automated, home, and ambulatory measurements. Volume overload is the consequence of a too excessive sodium intake and the impaired ability of the kidney to excrete sodium at normal arterial pressures. Renal artery stenosis also leads to diagnostic and therapeutic dilemmas. There are numerous studies in the literature about weight loss and its effects on BP, whether by dietary or pharmacological intervention or by bariatric surgery. Hypertension is not only prevalent in patients with CKD, it is also a key factor to control cardiovascular events in patients with CKD and to prevent progression of CKD itself.

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