Chapter 6

Nanotechnology-Based Applications for Transdermal Delivery of Therapeutics

Venkata K. Yellepeddi

Venkata K. Yellepeddi

College of Pharmacy, Roseman University of Health Sciences, South Jordan, UT, USA

College of Pharmacy, University of Utah, Salt Lake City, UT, USA

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Ryan F. Donnelly

Ryan F. Donnelly

School of Pharmacy, Queen's University Belfast, UK

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Thakur Raghu Raj Singh

Thakur Raghu Raj Singh

School of Pharmacy, Queen's University Belfast, UK

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First published: 15 July 2015
Citations: 4

Summary

Nanotechnology is considered to be one of the most important innovations in the field of modern medicine. Owing to its enormous success, nanotechnology was also investigated for its applications in delivery of therapeutics through skin. The complexity of skin's structural integrity poses a challenge for the delivery of nanoparticles with therapeutics through skin. Therefore, this contribution will attempt to provide a concise review of applications of nanotechnology with respect to delivery of therapeutics through skin. To this end, skin structure, pathways for nanoparticle penetration, current nanotechnology based formulations for skin delivery and limitations of nanotechnology for skin delivery applications will be reviewed.

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