Chapter 33
Clinical and Diagnostic Aspects of Viral Hepatitis
Cui Li Lin,
Chelsea Q. Xu,
Jack R. Wands,
Cui Li Lin
Warren Alpert Medical School of Brown University, Providence, RI, USA
Search for more papers by this authorChelsea Q. Xu
Warren Alpert Medical School of Brown University, Providence, RI, USA
Search for more papers by this authorJack R. Wands
Warren Alpert Medical School of Brown University, Providence, RI, USA
Search for more papers by this authorCui Li Lin,
Chelsea Q. Xu,
Jack R. Wands,
Cui Li Lin
Warren Alpert Medical School of Brown University, Providence, RI, USA
Search for more papers by this authorChelsea Q. Xu
Warren Alpert Medical School of Brown University, Providence, RI, USA
Search for more papers by this authorJack R. Wands
Warren Alpert Medical School of Brown University, Providence, RI, USA
Search for more papers by this authorBook Editor(s):Howard C. Thomas BSc, PhD, FRCP, FRCPath, FMedSci,
Anna S.F. Lok MD,
Stephen A. Locarnini MBBS, BSc(Hons), PhD, FRCPath,
Arie J. Zuckerman MD, DSc, FRCP, FRCPath, FMedSci,
Howard C. Thomas BSc, PhD, FRCP, FRCPath, FMedSci
Emeritus Professor of Hepatology, Department of Medicine, Imperial College London, London, UK
Search for more papers by this authorAnna S.F. Lok MD
Alice Lohrman Andrews Research Professor in Hepatology, Director of Clinical Hepatology, Professor of Internal Medicine, Associate Chair for Clinical Research, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, USA
Search for more papers by this authorStephen A. Locarnini MBBS, BSc(Hons), PhD, FRCPath
Head, Research & Molecular Development, Victorian Infectious Diseases Reference Laboratory, Melbourne, VIC, Australia
Search for more papers by this authorArie J. Zuckerman MD, DSc, FRCP, FRCPath, FMedSci
Emeritus Professor of Medical Microbiology, Formerly Principal and Dean, Royal Free Hospital School of Medicine
Search for more papers by this authorFirst published: 26 July 2013
Summary
Infections with viral hepatitis A through E have a variable clinical presentation ranging from asymptomatic or mild flulike symptoms to jaundice and fulminant liver failure. Hepatitis A and E are fecal-orally transmitted, resulting in acute infection that is mostly self-limited. In contrast, hepatitis B virus (HBV), hepatitis C virus (HCV), and hepatitis D virus (HDV) are acquired via sexual, vertical, and parenteral transmissions and can result in both acute and chronic infection. Testing for hepatitis A through E is based on serological and molecular tests.
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