Chapter 3
Oxidative Stress and its Biochemical Consequences in Mitochondrial DNA Mutation-Associated Diseases: Implications of Redox Therapy for Mitochondrial Diseases
Shi-Bei Wu,
Yu-Ting Wu,
Yi-Shing Ma,
Yau-Huei Wei,
Shi-Bei Wu
Department of Biochemistry and Molecular Biology, School of Life Sciences, National Yang-Ming University, Taipei, Taiwan
Search for more papers by this authorYu-Ting Wu
Department of Biochemistry and Molecular Biology, School of Life Sciences, National Yang-Ming University, Taipei, Taiwan
Search for more papers by this authorYi-Shing Ma
Department of Biochemistry and Molecular Biology, School of Life Sciences, National Yang-Ming University, Taipei, Taiwan
Search for more papers by this authorYau-Huei Wei
Department of Biochemistry and Molecular Biology, School of Life Sciences, National Yang-Ming University, Taipei, Taiwan
Department of Medicine, Mackay Medical College, New Taipei City, Taiwan
Search for more papers by this authorShi-Bei Wu,
Yu-Ting Wu,
Yi-Shing Ma,
Yau-Huei Wei,
Shi-Bei Wu
Department of Biochemistry and Molecular Biology, School of Life Sciences, National Yang-Ming University, Taipei, Taiwan
Search for more papers by this authorYu-Ting Wu
Department of Biochemistry and Molecular Biology, School of Life Sciences, National Yang-Ming University, Taipei, Taiwan
Search for more papers by this authorYi-Shing Ma
Department of Biochemistry and Molecular Biology, School of Life Sciences, National Yang-Ming University, Taipei, Taiwan
Search for more papers by this authorYau-Huei Wei
Department of Biochemistry and Molecular Biology, School of Life Sciences, National Yang-Ming University, Taipei, Taiwan
Department of Medicine, Mackay Medical College, New Taipei City, Taiwan
Search for more papers by this authorBook Editor(s):Tahira Farooqui,
Akhlaq A. Farooqui,
Tahira Farooqui
Department of Entomology/Center of Molecular Neurobiology, The Ohio State University, Columbus, Ohio, USA
Search for more papers by this authorAkhlaq A. Farooqui
Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio, USA
Search for more papers by this authorFirst published: 07 November 2011
Summary
This chapter contains sections titled:
-
Introduction
-
Mitochondrial DNA Mutationelicited Oxidative Stress
-
Mitochondrial DNA Mutation and Mitochondrial Diseases
-
Biochemical Consequences of mtDNA Mutation in Mitochondrial Diseases
-
Alteration of Antioxidant Defense System in Mitochondrial Diseases
-
Redox Therapy of Mitochondrial Diseases
-
Genetics-Based Gene Therapy for Mitochondrial Diseases
-
Conclusion
-
Acknowledgments
-
References
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