Chapter 4

AHR Ligands: Promiscuity in Binding and Diversity in Response

Danica DeGroot

Danica DeGroot

Department of Environmental Toxicology, University of California, Davis, CA, USA

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Guochun He

Guochun He

Department of Environmental Toxicology, University of California, Davis, CA, USA

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Domenico Fraccalvieri

Domenico Fraccalvieri

Dipartimento di Scienze dell' Ambiente e del Territorio, Università degli Studi di Milano-Bicocca, Milano, Italy

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Laura Bonati

Laura Bonati

Dipartimento di Scienze dell' Ambiente e del Territorio, Università degli Studi di Milano-Bicocca, Milano, Italy

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Allesandro Pandini

Allesandro Pandini

Division of Mathematical Biology, National Institute for Medical Research, London, UK

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Michael S. Denison

Michael S. Denison

Department of Environmental Toxicology, University of California, Davis, CA, USA

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First published: 10 November 2011
Citations: 23

Summary

This chapter contains sections titled:

  • The AH Receptor

  • AHR Ligands

  • AHR Ligand Binding Domain

  • Promiscuity in Ligand-Dependent AHR Activation

  • Conclusions

  • Acknowledgments

  • References

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