Chapter 12

Role of the AHR and its Structure in TCDD Toxicity

Raimo Pohjanvirta

Raimo Pohjanvirta

Department of Food Hygiene and Environmental Health, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland

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Merja Korkalainen

Merja Korkalainen

Department of Environmental Health, National Institute for Health and Welfare, Kuopio, Finland

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Ivy D. Moffat

Ivy D. Moffat

Department of Pharmacology and Toxicology, University of Toronto, Toronto, Canada

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Paul C. Boutros

Paul C. Boutros

Informatics and Biocomputing Platform, Ontario Institute for Cancer Research, MaRS Centre, Toronto, Ontario, Canada

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Allan B. Okey

Allan B. Okey

Department of Pharmacology and Toxicology, University of Toronto, Toronto, Canada

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First published: 10 November 2011
Citations: 5

Summary

This chapter contains sections titled:

  • Introduction

  • Toxicity of TCDD

  • Ligand Binding Domain

  • Transactivation Domain

  • Conclusions

  • Acknowledgments

  • References

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