Chapter 8

The Nature and Influence of Ultraviolet and Hydroxylamine Lesions in Nucleic Acids and the Enzymic Repair of the Former

Lawrence Grossman

Lawrence Grossman

Graduate Department of Biochemistry, Brandeis University, Waltham, Massachusetts, and University Chemical Laboratory, Cambridge

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Daniel M. Brown

Daniel M. Brown

Graduate Department of Biochemistry, Brandeis University, Waltham, Massachusetts, and University Chemical Laboratory, Cambridge

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First published: 01 January 1969
Citations: 2
Book Series:Novartis Foundation Symposia

Summary

The prelims comprise:

  • Modification of Polycytidylic Acid

  • Alteration By Hydroxylamine

  • Substrate Modifications

  • Induced Reiteration

  • Reduction of UTP

  • Enzymes Active in the Early Stages of Repair

  • Properties of U.V. Endonuclease (Incision Enzyme)

  • Properties of U.V. Exonuclease (Excision Enzyme)

  • Size of the Excised Regions

  • Involvement of Nucleases in Biological Repair

  • Summary

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