Chapter 20
G-Protein-Coupled Receptors as Drug Targets
Wenyan Miao,
Lijun Wu,
Wenyan Miao
Wyeth Inflammation, Wyeth Pharmaceuticals, Inc., Cambridge, Massachusetts, USA
Search for more papers by this authorLijun Wu
Resolvyx Pharmaceuticals, Inc., Bedford, Massachusetts, USA
Search for more papers by this authorWenyan Miao,
Lijun Wu,
Wenyan Miao
Wyeth Inflammation, Wyeth Pharmaceuticals, Inc., Cambridge, Massachusetts, USA
Search for more papers by this authorLijun Wu
Resolvyx Pharmaceuticals, Inc., Bedford, Massachusetts, USA
Search for more papers by this authorBook Editor(s):Chuang Lu,
Albert P. Li,
Chuang Lu
Department of DMPK, Millennium Pharmaceuticals, Inc., Cambridge, Massachusetts, USA
Search for more papers by this authorAlbert P. Li
In Vitro ADMET Laboratories, Columbia, Maryland, USA
Search for more papers by this authorFirst published: 14 December 2009
Summary
This chapter contains sections titled:
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Introduction
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GPCR Classes and Structures
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GPCR Signaling
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GPCR Pharmacology
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GPCR Assays for drug Discovery
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Challenges and Opportunities for GPCR Drug Discovery
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GPCRs as Drug Targets in Inflammation
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GPCRs as Drug Targets in Obesity
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Conclusions and Perspectives
-
References
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