Chapter 16

Polymorphisms of Drug Transporters and Their Clinical Implications

Cindy Q. Xia

Cindy Q. Xia

Department of DMPK, Millennium Pharmaceuticals, Inc., Cambridge, Massachusetts, USA

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Johnny J. Yang

Johnny J. Yang

Department of DMPK, Millennium Pharmaceuticals, Inc., Cambridge, Massachusetts, USA

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First published: 14 December 2009
Citations: 1

Summary

This chapter contains sections titled:

  • Introduction

  • Genetic Polymorphisms Of MDR 1 (P-gp) and their Implications

  • Genetic Polymorphisms of MRP and their Implications

  • Genetic Polymorphisms of BCRP and their Implications

  • Genetic Polymorphisms of OATP (SLC 21) and their Implications

  • Genetic Polymorphisms of OAT and OCT (SLC 22) and their Implications

  • Genetic Polymorphisms of PEPT (SLC 15) and their Implications

  • Summary

  • References

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