This chapter contains sections titled:

• Overview

• History and Clinical Picture of Anxiety Disorders

• Genetic Contributions to Anxiety Disorders

• Animal Models of Anxiety

• Pathophysiology of Anxiety Disorders

• Emotional Regulation: Role for the mPFC

• Therapeutic Targets: The Neurobiology of Coping

• Vulnerability for Anxiety Disorders

• Developmental Origins of Vulnerability for Anxiety Disorders

• Familial Transmission of Risk: Effects of Genes, Environment, and Their Interaction

• Conclusions

• References

• Further Reading