Chapter 15

Evolution of Antigenic Variation

Steven A. Frank Ph.D.

Steven A. Frank Ph.D.

Professor of Biology

Department of Ecology and Evolutionary Biology, University of California, Irvine, CA 92697–2525, USA http://stevefrank.org

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First published: 07 August 2006

This chapter is a condensed version of my book, Immunology and Evolution of Infectious Disease, Princeton University Press, Princeton, NJ, 2002.

Summary

This chapter contains sections titled:

  • Introduction

  • Why Do Parasites Vary?

  • Mechanisms that Generate Variation

  • Interactions with Host Immunity

  • Experimental Evolution

  • Measuring Selection with Population Samples

  • Shape, Charge, Binding Kinetics, and Evolution

  • Abbreviations

  • Glossary

  • References

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