Murein (Peptidoglycan)
Part 5. Polysaccharides
Dr. Christoph Heidrich,
Dr. Waldemar Vollmer,
Dr. Christoph Heidrich
- [email protected]
- +49-0211-9024 302 | Fax: +49-0211-9024 480
Landesunfallkasse NRW, Abteilung Prävention, Ulenbergstrasse 1, Düsseldorf, Germany, D-40223
Search for more papers by this authorDr. Waldemar Vollmer
- [email protected]
- +49-7071-601 466 | Fax: +49-7071-601 447
Max-Planck-Institut für Entwicklungsbiologie, Abteilung Biochemie, Spemannstraße 35/II, Tübingen, D-72076
Search for more papers by this authorDr. Christoph Heidrich,
Dr. Waldemar Vollmer,
Dr. Christoph Heidrich
- [email protected]
- +49-0211-9024 302 | Fax: +49-0211-9024 480
Landesunfallkasse NRW, Abteilung Prävention, Ulenbergstrasse 1, Düsseldorf, Germany, D-40223
Search for more papers by this authorDr. Waldemar Vollmer
- [email protected]
- +49-7071-601 466 | Fax: +49-7071-601 447
Max-Planck-Institut für Entwicklungsbiologie, Abteilung Biochemie, Spemannstraße 35/II, Tübingen, D-72076
Search for more papers by this authorFirst published: 15 January 2005
Abstract
- Introduction
- Historical Outline
- Isolation, Analysis and Structure of Murein
- Isolation of Murein
- The Basic Chemical Structure of Murein
- Species-specific Structural Variation (Murein Types)
- Secondary Modifications in the Murein Structure
- Covalent Attachment of Cell Wall Components to the Murein Sacculus
- The Fine Structure of Murein
- Analysis of the Length Distribution of the Murein Glycan Strands
- Analysis of the Muropeptide Composition
- Variability of the Species-specific Murein Composition
- Three-dimensional Structure of Murein
- Biosynthesis of Murein
- Biosynthesis of the Murein Precursor Lipid II
- Formation of UDP-MurNAc(pentapeptide) in the Cytoplasm
- Formation of the Lipid Intermediates
- Murein Synthases and Hydrolases
- Growth Mechanism of the Murein Sacculus
- Safe Strategies for the Enlargement of the Stress-bearing Murein
- “Three-for-one” Model (Höltje, 1996) “Three-for-one” Model
- Recycling of the Turnover Products
- Inhibition of Murein Biosynthesis
- Biosynthesis of the Murein Precursor Lipid II
- Molecular Genetics of Murein Biosynthesis
- Exogenous Murein Hydrolases
- Biological Activities of Murein
- Production
- Current Problems and Outlook
- Acknowledgments
References
- Allmaier, G., Schmid, E. R. (1993) New mass spectrometric methods for peptidoglycan analysis, in: Bacterial Growth and Lysis: Metabolism and Structure of the Bacterial Sacculus ( M. A. de Pedro, J.-V. Höltje, W. Löffelhardt, Eds.), London/New York: Plenum Press, 23–30.
- Arthur, M., Reynolds, P., Courvalin, P. (1996) Glycopeptide resistance in enterococci, Trends Microbiol. 4, 401–407.
- Atrih, A., Foster, S. J. (1999) The role of peptidoglycan structure and structural dynamics during endospore dormancy and germination, Antonie Van Leeuwenhoek 75, 299–307.
- Barnikel, G., Naumann, D., Bradaczek, H., Labischinski, H., Giesbrecht, P. (1983) Computer aided molecular modelling of the three-dimensional structure of bacterial peptidoglycan, in: The Target of Penicillin: The Murein Sacculus of Bacterial Cell Walls. Architecture and Growth ( R. Hakenbeck, J.-V. Höltje, H. Labischinski, Eds.), Berlin/New York: de Gruyter, 61–66.
- Boneca, I. G., Huang, Z. H., Gage, D. A., Tomasz, A. (2000) Characterization of Staphylococcus aureus cell wall glycan strands, evidence for a new beta-N-acetylglucosaminidase activity, J. Biol. Chem. 275, 9910–9918.
- Braun, V. (1975) Covalent lipoprotein from the outer membrane of Escherichia coli, Biochim. Biophys. Acta 415, 335–377.
- Caparros, M., Pisabarro, A. G., de Pedro, M. A. (1992) Effect of D-amino acids on structure and synthesis of peptidoglycan in Escherichia coli, J. Bacteriol. 174, 5549–5559.
- Chapman, G. P., Hillier, J. (1953) Electron microscopy of ultra-thin sections of bacteria. I. Cellular division in Bacillus cereus, J. Bacteriol. 66, 362–373.
- Clarke, A. J., Dupont, C. (1992) O-acetylated peptidoglycan: its occurrence, pathobiological significance, and biosynthesis, Can. J. Microbiol. 38, 85–91.
- Demchick, P., Koch, A. L. (1996) The permeability of the wall fabric of Escherichia coli and Bacillus subtilis, J. Bacteriol. 178, 768–773.
- Ellouz, F., Adam, A., Ciorbaru, R., Lederer, E. (1974) Minimal structural requirement for adjuvant activity of bacterial peptidoglycan derivatives, Biochem. Biophys. Res. Commun. 59, 1317–1325.
- Filipe, S. R., Tomasz, A. (2000) Inhibition of the expression of penicillin resistance in Streptococcus pneumoniae by inactivation of cell wall muropeptide branching genes, Proc. Natl. Acad. Sci. USA 97, 4891–4896.
- Garcia, P., Gonzalez, M. P., Garcia, E., Lopez, R., Garcia, J. L. (1999) LytB, a novel pneumococcal murein hydrolase essential for cell separation, Mol. Microbiol. 31, 1275–1277.
- Ghuysen, J. M. (1991) Serine beta-lactamases and penicillin-binding proteins, Annu. Rev. Microbiol. 45, 37–67.
- Glauner, B. (1988) Separation and quantification of muropeptides with high-performance liquid chromatography, Anal. Biochem. 172, 451–464.
- Glauner, B., Höltje, J.-V. (1990) Growth pattern of the murein sacculus of Escherichia coli, J. Biol. Chem. 265, 18988–18996.
- Glauner, B., Höltje, J.-V., Schwarz, U. (1988) The composition of the murein of Escherichia coli, J. Biol. Chem. 263, 10088–10095.
- Goodell, E. W. (1985) Recycling of murein by Escherichia coli, J. Bacteriol. 163, 305–310.
- Goodell, E. W., Higgins, C. F. (1987) Uptake of cell wall peptides by Salmonella typhimurium and Escherichia coli, J. Bacteriol. 169, 3861–3865.
- Goodell, E. W., Schwarz, U. (1985) Release of cell wall peptides into culture medium by exponentially growing Escherichia coli, J. Bacteriol. 162, 391–397.
- Harz, H., Burgdorf, K., Höltje, J.-V. (1990) Isolation and separation of the glycan strands from murein of Escherichia coli by reversed-phase high-performance liquid chromatography, Anal. Biochem. 190, 120–128.
- Hayashi, H., Araki, Y., Ito, E. (1973) Occurrence of glucosamine residues with free amino groups in cell wall peptidoglycan from bacilli as a factor responsible for resistance to lysozyme, J. Bacteriol. 113, 592–598.
- Höltje, J.-V. (1995) From growth to autolysis: the murein hydrolases in Escherichia coli, Arch. Microbiol. 164, 243–254.
- Höltje, J.-V. (1996) Molecular interplay of murein synthases and murein hydrolases in Escherichia coli, Microb. Drug Resist. 2, 99–103.
- Höltje, J.-V. (1998) Growth of the stress-bearing and shape-maintaining murein sacculus of Escherichia coli, Microbiol. Mol. Biol. Rev. 62, 181–203.
- Höltje, J.-V., Schwarz, U. (1985) Biosynthesis and growth of the murein sacculus, in: Molecular Cytology of Escherichia coli ( N. Nanninga, Ed.), London: Academic Press, 77–119.
- Höltje, J.-V., Mirelman, D., Sharon, N., Schwarz, U. (1975) Novel type of murein transglycosylase in Escherichia coli, J. Bacteriol. 124, 1067–1076.
- Höltje, J.-V., Kopp, U., Ursinus, A., Wiedemann, B. (1994) The negative regulator of β-lactamase induction AmpD is a N-acetyl-anhydromuramyl-L-amidase, FEMS Microbiol. Lett. 122, 159–164.
- Jacobs, C., Frere, J. M., Normark, S. (1997) Cytosolic intermediates for cell wall biosynthesis and degradation control inducible beta-lactam resistance in Gram-negative bacteria, Cell 88, 823–832.
- Jacobs, T., Leippe, M. (1995) Purification and molecular cloning of a major antibacterial protein of the protozoan parasite Entamoeba histolytica with lysozyme-like properties, Eur. J. Biochem. 231, 831–838.
-
Jolles, P. (Ed.)
(1996)
Lysozymes: Model enzymes in Biochemistry and Biology, Basel: Birkhäuser.
10.1007/978-3-0348-9225-4 Google Scholar
- Kang, D., Liu, G., Lundstrom, A., Gelius, E., Steiner, H. (1998) A peptidoglycan recognition protein in innate immunity conserved from insects to humans, Proc. Natl. Acad. Sci. USA 95, 10078–10082.
- Koch, A. L., Doyle, R. J. (1985) Inside-to-outside growth and turnover of the wall of Gram-positive rods, J. Theor. Biol. 117, 137–157.
- Kraft, A. R., Prabhu, J., Ursinus, A., Höltje, J.-V. (1999) Interference with murein turnover has no effect on growth but reduces beta-lactamase induction in Escherichia coli, J. Bacteriol. 181, 7192–7198.
- Labischinski, H., Barnikel, G., Naumann, D. (1983) The state of order of bacterial peptidoglycan, in: The Target of Penicillin: The Murein Sacculus of Bacterial Cell Walls. Architecture and Growth ( R. Hakenbeck, J.-V. Höltje, H. Labischinski, Eds.), Berlin/New York: de Gruyter, 49–54.
- Labischinski, H., Goodell, E. W., Goodell, A., Hochberg, M. L. (1991) Direct proof of a ‘more-than-single-layered’ peptidoglycan architecture of Escherichia coli W7: a neutron small-angle scattering study, J. Bacteriol. 173, 751–756.
-
Lancini, G.,
Parenti, F.,
Gallo, G. G.
(1995)
Antibiotics: A Multidisciplinary Approach, New York: Plenum Press.
10.1007/978-1-4757-9200-3 Google Scholar
- Lichenstein, H. S., Hastings, A. E., Langley, K. E., Mendiaz, E. A., Rohde, M. F., Elmore, R., Zukowski, M. M. (1990) Cloning and nucleotide sequence of the N-acetylmuramidase M1-encoding gene from Streptomyces globisporus, Gene 88, 81–86.
- Lyne, J. E., Carter, D. C., He, X. M., Stubbs, G., Hash, J. H. (1990) Preliminary crystallographic examination of a novel fungal lysozyme from Chalaropsis, J. Biol. Chem. 265, 6928–6930.
- Mainardi, J. L., Legrand, R., Arthur, M., Schoot, B., van Heijenoort, J., Gutmann, L. (2000) Novel mechanism of beta-lactam resistance due to bypass of DD-transpeptidation in Enterococcus faecium, J. Biol. Chem. 275, 16490–16496.
-
Matsuhashi, M.
(1994)
Utilization of lipid-linked precursors and the formation of peptidoglycan in the process of cell growth and division: membrane enzymes involved in the final steps of peptidoglycan synthesis and the mechanism of their regulation, in: Bacterial cell wall, New Comprehensive Biochemistry Vol. 27 ( J.-M. Ghuysen, R. Hakenbeck, Eds.), Amsterdam: Elsevier Science B. V.,
55–71.
10.1016/S0167-7306(08)60407-X Google Scholar
- Murray, R. G. E., Steed, P., Elson, H. E. (1965) Location of mucopeptide in sections of cell wall of Escherichia coli and other Gram-negative bacteria, Can. J. Microbiol. 11, 547–560.
- Navarre, W. W., Schneewind, O. (1999) Surface proteins of Gram-positive bacteria and mechanisms of their targeting to the cell wall envelope, Microbiol. Mol. Biol. Rev. 63, 174–229.
- Norris, V., Manners, B. (1993) Deformations in the cytoplasmic membrane of Escherichia coli direct the synthesis of peptidoglycan. The hernia model, Biophys. J. 64, 1691–1700.
- Oshida, T., Sugai, M., Komatsuzawa, H., Hong, Y. M., Suginaka, H., Tomasz, A. (1995) A Staphylococcus aureus autolysin that has an N-acetylmuramoyl-L-alanine amidase domain and an endo-beta-N-acetylglucosaminidase domain: cloning, sequence analysis, and characterization, Proc. Natl. Acad. Sci. USA 92, 285–289.
- Pellegrini, M., Marcotte, E. M., Thompson, M. J., Eisenberg, D., Yeates, T. O. (1999) Assigning protein functions by comparative genome analysis: protein phylogenetic profiles, Proc. Natl. Acad. Sci. USA 96, 4285–4288.
- Park, J. T. (1996) The convergence of murein recycling research with β-lactamase research, Microb. Drug Resist. 2, 105–112.
- Park, J. T., Burman, L. G. (1985) Elongation of the murein sacculus of Escherichia coli, Ann. Inst. Pasteur Microbiol. 136A, 51–58.
- Park, J. T., Raychaudhuri, D., Li, H., Normark, S., Mengin-Lecreulx, D. (1998) MppA, a periplasmic binding protein essential for import of the bacterial cell wall peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate, J. Bacteriol. 180, 1215–1223.
- Rietschel, E. T., Schletter, J., Weidemann, B., El-Samalouti, V., Mattern, T., Zahringer, U., Seydel, U., Brade, H., Flad, H. D., Kusumoto, S., Gupta, D., Dziarski, R., Ulmer, A. J. (1998) Lipopolysaccharide and peptidoglycan: CD14-dependent bacterial inducers of inflammation, Microb. Drug Resist., 4, 37–44.
- Romeis, T., Höltje, J.-V. (1994) Specific interaction of penicillin-binding proteins 3 and 7/8 with soluble lytic transglycosylase in Escherichia coli, J. Biol. Chem. 269, 21603–21607.
-
Salton, M. R. J.
(1994)
The bacterial cell envelope – a historical perspective, in: Bacterial Cell Wall, New Comprehensive Biochemistry, Vol. 27 ( J.-M. Ghuysen, R. Hakenbeck, Eds.), Amsterdam: Elsevier Science B. V.,
1–22.
10.1016/S0167-7306(08)60404-4 Google Scholar
- Salton, M. R. J., Horne, R. W. (1951) Studies of the bacterial cell wall. 2. Methods of preparation and some properties of cell walls, Biochim. Biophys. Acta 7, 177–197.
- Schleifer, K. H., Kandler, O. (1972) Peptidoglycan types of bacterial cell walls and their taxonomic implications, Bacteriol. Rev. 36, 407–477.
- Seidl, P. H., Schleifer, K. H. (Eds.) (1986) Biological Properties of Peptidoglycan, Berlin/New York: de Gruyter.
- Shockman, G. D., Barrett, J. F. (1983) Structure, function, and assembly of cell walls of Gram-positive bacteria, Annu. Rev. Microbiol. 37, 501–527.
-
Shockman, G. D.,
Höltje, J.-V.
(1994)
Bacterial peptidoglycan (murein) hydrolases, in: Bacterial Cell Wall, New Comprehensive Biochemistry, Vol. 27 ( J.-M. Ghuysen, R. Hakenbeck, Eds.), Amsterdam: Elsevier Science B. V.,
131–166.
10.1016/S0167-7306(08)60410-X Google Scholar
- Sieradzki, K., Tomasz, A. (1997) Inhibition of cell wall turnover and autolysis by vancomycin in a highly vancomycin-resistant mutant of Staphylococcus aureus, J. Bacteriol. 179, 2557–2566.
- Sudo, S., Dworkin, M. (1972) Bacteriolytic enzymes produced by Myxococcus xanthus, J. Bacteriol. 110, 236–245.
- Templin, M., Ursinus, A., Höltje, J.-V. (1999) A defect in cell wall recycling triggers autolysis during the stationary growth phase of Escherichia coli, EMBO J. 18, 4108–4117.
- van Heijenoort, J. (1998) Assembly of the monomer unit of bacterial peptidoglycan, Cell. Mol. Life Sci. 54, 300–304.
- Vicente, M., Gomez, M. J., Ayala, J. A. (1998) Regulation of transcription of cell division genes in the Escherichia coli dcw cluster, Cell. Mol. Life Sci. 54, 317–324.
- Vötsch, W., Templin, M. (2000) Characterization of a β-N-acetylglucosaminidase of Escherichia coli and elucidation of its role in muropeptide recycling and β-lactamase induction, J. Biol. Chem. 275, 39032–39038.
- Vollmer, W., Tomasz, A. (2000) The pgdA gene encodes for a peptidoglycan N-acetylglucosamine deacetylase in Streptococcus pneumoniae, J. Biol. Chem. 275, 20496–20501.
- Vollmer, W., von Rechenberg, M., Höltje, J.-V. (1999) Demonstration of molecular interactions between the murein polymerase PBP1B, the lytic transglycosylase MltA, and the scaffolding protein MipA of Escherichia coli, J. Biol. Chem. 274, 6726–6734.
- von Rechenberg, M., Ursinus, A., Höltje, J.-V. (1996) Affinity chromatography as a means to study multienzyme complexes involved in murein synthesis, Microb. Drug Resist. 2, 155–157.
- Weidel, W., Pelzer, H. (1964) Bagshaped macromolecules – a new outlook on bacterial cell walls, Adv. Enzymol. 26, 193–232.
- Yamada, S., Sugai, M., Komatsuzawa, H., Nakashima, S., Oshida, T., Matsumoto, A., Suginaka, H. (1996) An autolysin ring associated with cell separation of Staphylococcus aureus, J. Bacteriol. 178, 1565–1571.
- Young, R. (1992) Bacteriophage lysis: mechanism and regulation, Microbiol. Rev. 56, 430–481.
- Zipperle, G. F., Jr., Ezzell, J. W., Jr., Doyle, R. J. (1984) Glucosamine substitution and muramidase susceptibility in Bacillus anthracis, Can. J. Microbiol. 30, 553–559.
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