Extracellular Polyhydroxyalkanoate (PHA) Depolymerases: The Key Enzymes of PHA Degradation
Part 3b. Polyesters
Priv.-Doz. Dr. rer. nat. Dieter Jendrossek,
Priv.-Doz. Dr. rer. nat. Dieter Jendrossek
- [email protected]
- +49-711-685-5483 | Fax: +49-711-685-5725
Institut für Mikrobiologie der Universität Stuttgart, Allmandring 31, Stuttgart, Germany, D-70569
Search for more papers by this authorPriv.-Doz. Dr. rer. nat. Dieter Jendrossek,
Priv.-Doz. Dr. rer. nat. Dieter Jendrossek
- [email protected]
- +49-711-685-5483 | Fax: +49-711-685-5725
Institut für Mikrobiologie der Universität Stuttgart, Allmandring 31, Stuttgart, Germany, D-70569
Search for more papers by this authorAbstract
- Introduction
- Historical Outline
- Identification and Isolation of Extracellular d-Poly(HA)-Degrading Microorganisms
- Characterization of Poly(HA)-Degrading Microorganisms
- Biochemical Properties of Extracellular d-Poly(HA) Depolymerases
- Molecular Biology and Functional Analysis of d-Poly(3HASCL) Depolymerases
- PhaZ7, a new Type of Thermoalkalophilic Hydrolase of P. lemoignei with high Specificity for Amorphous Poly(HASCL)
- Molecular Biology and Functional Analysis of d-Poly(HAMCL) Depolymerases
- Enantioselectivity and Hydrolysis Products of Poly(HA) Depolymerases
- Regulation of Poly(HA) Depolymerase Synthesis
- Influence of Physico-chemical Properties of the Polymer on its Biodegradability
- Outlook and Perspectives
- Patents
- Acknowledgments
References
- Abe, H., Doi, Y. (1996) Enzymatic and environmental degradation of racemic poly(3-hydroxybutyric acid)s with different stereoregulators, Macromolecules 29, 8683–8688.
- Abe, H., Doi, Y. (1999) Structural effects on enzymatic degradabilities for poly(R)-3-hydroxybutyric acid] and its copolymers, Int. J. Biol. Macromol. 25, 185–192.
- Abe, H., Matsubara, I., Doi, Y., Hori, Y., Yamaguchi, A. (1994) Physical properties and enzymatic degradability of poly(3-hydroxybutyrate) stereoisomers with different stereoregularities, Macromolecules 27, 6018–6025.
- Abe, H., Matsubara, I., Doi, Y. (1995) Physical properties and enzymatic degradability of polymer blends of bacterial poly[(R)-3-hydroxybutyrate] and poly[(R,S)-3-hydroxybutyrate] stereoisomers, Macromolecules 28, 844–853.
- Akutsu, T., Nakajima-Kambe, T., Nomura, N., Nakahara, T. (1998) Purification of a polyester polyurethane-degrading enzyme from Comamonas acidovorans TB-35, Appl. Environ. Microbiol. 64, 62–67.
- Amor, S. R., Rayment, T., Sanders, J. K. M. (1991) Poly(3-hydroxybutyrate) in vivo: NMR and X-ray characterization of the elastomeric state, Macromolecules 24, 4583–4588.
- Anderson, A. J., Dawes, E. A. (1990) Occurrence, metabolism, metabolic role, and industrial use of bacterial poly-hydroxyalkanoates, Microbiol. Rev. 54, 450–472.
- Arpigny, J.-L., Jaeger, K.-E. (1999) Bacterial lipolytic enzymes: classification and properties, Biochem. J. 343, 177–183.
-
Babel, W.,
Ackermann, J.-U.,
Breuer, U.
(2001)
Physiology, regulation and limits of the synthesis of poly(3HB), in: Biopolyesters, Advances in Biochemical Engineering/Biotechnology ( T. Scheper, Ed.), Berlin, Heidelberg: Springer-Verlag,
125–158.
10.1007/3-540-40021-4_4 Google Scholar
- Bachmann, B. M., Seebach, D. (1999) Investigation of the enzymatic cleavage of diastereomeric oligo(3-hydroxybutanoates) containing two to eight HB subunits. A model for the stereoselectivity of PHB depolymerase from Alcaligenes faecalis, Macromolecules 32, 1777–1784.
- Behrends, A., Klingbeil, B., Jendrossek, D. (1996) Poly(3-hydroxybutyrate) depolymerases bind to their substrate by a C-terminal located substrate binding site, FEMS Microbiol. Lett. 143, 191–194.
-
Brandl, H.,
Püchner, P.
(1992)
Biodegradation of plastic bottles made from ‘Biopol’ in an aquatic ecosystem under in situ conditions,
Biodegradation 2,
237–243.
10.1007/BF00114555 Google Scholar
- Brandl, H., Aeberli, B., Bachofen, R., Schwegler, I., Müller, H.-M., Bürger, M. H., Hoffmann, T., Lengweiler, U. D., Seebach, D. (1995a) Biodegradation of cyclic and substituted linear oligomers of poly(3-hydroxybutyrate), Can. J. Microbiol. 41 (Suppl. 1), 180–186.
- Brandl, H., Bachhofen, R., Mayer, J., Wintermantel, E. (1995b) Degradation and applications of polyhydroxyalkanoates, Can. J. Microbiol. 41 (Suppl. 1), 143–153.
- Braunegg, G., Lefebvre, G., Genser, K. F. (1998) Polyhydroxyalkanoates, biopolyesters from renewable resources: physiological and engineering aspects, J. Biotechnol. 65, 127–161.
- Briese, B.-H., Jendrossek, D. (1998) Biological basis of enzyme-catalyzed polyester degradation: 59 C-terminal amino acids of poly(3-hydroxybutyrate) (PHB) depolymerase A from Pseudomonas lemoignei are sufficient for PHB binding, Macromol. Symp. 130, 205–216.
- Briese, B.-H., Jendrossek, D., Schlegel, H. G. (1994a) Degradation of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) by aerobic sewage sludge, FEMS Microbiol. Lett. 117, 107–112.
- Briese, B.-H., Schmidt, B., Jendrossek, D. (1994b) Pseudomonas lemoignei has five poly(hydroxyalkanoic acid) (PHA) depolymerase genes: a comparative study of bacterial and eukaryotic depolymerases, J. Environ. Polym. Degrad. 2, 75–87.
- Brucato, C. L., Wong, S. S. (1991) Extracellular poly(3-hydroxybutyrate) depolymerase from Penicillium funiculosum: general characteristics and active site studies, Arch. Biochem. Biophys. 290, 497–502.
- Budwill, K., Fedorak, P. M., Page, W. J. (1992) Methanogenic degradation of poly(3-hydroxyalkanoates), Appl. Environ. Microbiol. 58, 1398–1401.
- Chowdhury, A. A. (1963) Poly-β-hydroxybuttersäure abbauende Bakterien und Exoenzym, Arch. Mikrobiol. 47, 167–200.
- Cornibert, J., Marchessault, R. H. (1975) Conformational Isomorphism. A general 2(1) helical conformation for poly(β-alkanoates), Macromolecules 8, 296–305.
- de Koning, G. J. M., Lemstra, P. J. (1992) The amorphous state of bacterial poly[(R)-3-hydroxyalkanoate)] in vivo, Polymer 33, 3304–3306.
- de Koning, G. J. M., van Bilsen, H. M. M., Lemstra, P. J., Hazenberg, W., Witholt, B., Preusting, H., van der Galien, J. G., Schirmer, A., Jendrossek, D. (1994) A biodegradable rubber by cross linking polyhydroxyalkanoates from Pseudomonas oleovorans, Polymer 35, 2090–2097.
- Delafield, F. P., Cooksey, K. E., Doudoroff, M. (1965a) β-hydroxybutyric dehydrogenase and dimer hydrolase of Pseudomonas lemoignei, J. Biol. Chem. 240, 4023–4028.
- Delafield, F. P., Doudoroff, M., Palleroni, N. J., Lusty, C. J., Contopoulos, R. (1965b) Decomposition of poly-β-hydroxybutyrate by pseudomonads, J. Bacteriol. 90, 1455–1466.
- Doi, Y. (1990) Microbial Polyesters, New York: VCH.
- Doi, Y., Kitamura, S., Abe, H. (1995) Microbial synthesis and characterization of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate), Macromolecules 28, 4822–4828.
- Doi, Y., Kanesawa, Y., Kunioka, M., Saito, T. (1990) Biodegradation of microbial copolyesters: poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and poly(3-hydroxybutyrate-co-4-hydroxybutyrate), Macromolecules 23, 26–31.
- Doi, Y., Kumagai, Y., Tanahashi, N., Mukai, K. (1992) Structural effects on biodegradation of microbial and synthetic poly(hydroxyalkanoates), in: Biodegradable Polymers and Plastics ( M. Vert, Ed.), London: Royal Society of Chemistry, 139–148.
-
Doi, Y.,
Mukai, K.,
Kasuya, K.,
Yamada, K.
(1994)
Biodegradation of biosynthetic and chemosynthetic poly-hydroxyalkanoates, in: Biodegradable Plastics and Polymers ( Y. Doi, K. Fukuda, Eds.), Amsterdam: Elsevier Science, BV,
39–51.
10.1016/B978-0-444-81708-2.50010-5 Google Scholar
- Eggert, T., Pencreac'h, G., Douchet, I., Verger, R., Jaeger, K.-E. (2000) A novel extracellular esterase from Bacillus subtilis and its conversion to a monoacylglycerol hydrolase, Eur. J. Biochem. 267, 6459–6496.
- Focarete, M. L., Ceccorulli, G., Scandola, M., Kowalczuk, M. (1998) Further evidence of crystallinity-induced biodegradation of synthetic atactic poly(3-hydroxybutyrate) by PHB-depolymerase A from Pseudomonas lemoignei. Blends of atactic poly(3-hydroxybutyrate) with crystalline polyesters, Macromolecules 31, 8485–8492.
- Focarete, M. L., Scandola, M., Jendrossek, D., Adamus, G., Sikorska, W., Kowalczuk, M. (1999) Bioassimilation of oligomers of atactic poly[(R,S)-3-hydroxybutyrate] by selected bacterial strains, Macromolecules 32, 4814–4818.
- Foster, L. J. R., Zervas, S. J., Lenz, R. W., Fuller, R. C. (1995) The biodegradation of poly-3-hydroxyalkanoates, PHAs, with long alkyl substituents by Pseudomonas maculicola, Biodegradation 6, 67–73.
- Fukui, T., Narikawa, T., Miwa, K., Shirakura, Y., Saito, T., Tomita, K. (1988) Effect of limited tryptic modification of a bacterial poly(3-hydroxybutyrate) depolymerase on its catalytic activity, Biochim. Biophys. Acta 952, 164–171.
- Gilbert, E. J. (1993) Pseudomonas lipases: biochemical properties and molecular cloning, Enzyme Microb. Technol. 15, 634–645.
- Gödde, C., Liebergesell, M., Steinbüchel, A. (1999) Isolation of poly(β-l-malic acid)-degrading bacteria and purification and characterization of the PMA hydrolase from Comamonas acidovorans strain 7789, FEMS Microbiol. Lett. 173, 365–372.
- Gonda, K. E., Jendrossek, D., Molitoris, H. P. (2000) Fungal degradation of thermoplastic polymers under simulated deep sea conditions, Hydrobiologia 426, 173–183.
- Gorenflo, V., Steinbüchel, A., Marose, S., Rieseberg, M., Scheper, T. (1999) Quantification of bacterial polyhydroxyalkanoates by Nile red staining, Appl. Microbiol. Biotechnol. 51, 765–772.
- Griebel, R. J., Merrick, J. M. (1971) Metabolism of poly-β-hydroxybutyrate: effect of mild alkaline extraction on native poly-β-hydroxybutyrate granules, J. Bacteriol. 108, 782–789.
- Griebel, R., Smith, Z., Merrick, J. M. (1968) Metabolism of poly-β-hydroxybutyrate. I. Purification, composition, and properties of native poly-β-hydroxybutyrate granules from Bacillus megaterium, Biochemistry 7, 3676–3681.
- Gruchulski, P., Bouthillier, F., Kazlauskas, R. J., Serreqi, A. N., Schrag, J. D., Ziomek, E., Cygler, M. (1994) Analogs of reaction intermediates identify a unique substrate binding site in Candida rugosa lipase, Biochemistry 33, 3494–3500.
- Han, J.-S., Son, Y.-J., Chang, C.-S., Kim, M.-N. (1998) Purification and properties of extracellular poly(3-hydroxybutyrate) depolymerase produced by Penicillium pinophilum, J. Microbiol. 36, 67–73.
- Handrick, R., Jendrossek, D. (1998) Extracellular and intracellular polyhydroxyalkanoate depolymerases: homologies and differences, in: Biochemical Principles and Mechanisms of Biodegradation and Biodegradation of Polymers ( A. Steinbüchel, Ed.), Weinheim, Germany: Wiley-VCH, 57–67.
- Handrick, R., Reinhardt, S., Jendrossek, D. (2000) Mobilization of poly(3-hydroxybutyrate) in Ralstonia eutropha, J. Bacteriol. 182, 5916–5918.
- Handrick, R., Reinhardt, S., Focarete, M. L., Scandola, M., Adamus, G., Kowalczuk, M., Jendrossek, D. (2001) A new type of thermoalkalophilic hydrolase of Paucimonas lemoignei with high specificity for amorphous polyesters of short-chain-length hydroxyalkanoic acids, J. Biol. Chem. 276, 36216–36224.
- Hippe, H. (1967) Aufbau und Wiederwerwertung von Poly-β-hydroxybuttersäure durch Hydrogenomonas H16, Arch. Mikrobiol. 56, 248–277.
- Hippe, H., Schlegel, H. G. (1967) Hydrolyse von PHBS durch intracelluläre Depolymerase von Hydrogenomonas H16, Arch. Mikrobiol. 56, 278–299.
- Hirashi, T., Ohura, T., Ito, S., Kassuya, K.-I., Doi, Y. (2000) Function of the catalytic domain of poly(3-hydroxybutyrate) depolymerase from Pseudomonas stutzeri, Biomacromolecules 1, 320–324.
- Hocking, P. J., Timmins, M. R., Scherer, T. M., Fuller, R. C., Lenz, R. W., Marchessault, R. H. (1995) Enzymatic degradability of poly(β-hydroxybutyrate) as a function of tacticity, J. Macromol. Sci., Pure Appl. Chem. A32, 889–894.
- Horowitz, D. M., Sanders, J. K. M. (1994) Amorphous, biomimetic granules of polyhydroxybutyrate: preparation, characterization, and biological implications, J. Am. Chem. Soc. 116, 2695–2702.
- Horowitz, D. M., Sanders, J. K. M. (1995) Biomimetic, amorphous granules of polyhydroxyalkanoates: composition, mobility, and stabilization in vivo by proteins, Can. J. Microbiol. 41 (Suppl. 1), 115–123.
- Horowitz, D. M., Brennan, E. M., Koon, J. J., Gerngross, T. U. (1999) Novel thermal route to an amorphous, film-forming polymer latex, Macromolecules 32, 3347–3352.
- Iwata, T., Doi, Y., Kasuya, K., Inoue, Y. (1997a) Visualization of enzymatic degradation of poly[(R)-3-hydroxybutyrate] single crystals by an extracellular PHB depolymerase, Macromolecules 30, 833–839.
- Iwata, T., Doi, Y., Tanaka, T., Akehata, T., Shiromo, M., Teramachi, S. (1997b) Enzymatic degradation and adsorption on poly[(β-3-hydroxybutyrate] single crystals with two types of extracellular PHB depolymerases from Comamonas acidovorans YM1609 and Alcaligenes faecalis T1, Macromolecules 30, 5290–5296.
- Iwata, T., Doi, Y., Nakayama, S.-I., Sasatsuki, H., Teramachi, S. (1999) Structure and enzymatic degradation of poly(3-hydroxybutyrate) copolymer single crystals with an extracellular PHB depolymerase from Alcaligenes faecalis T1, Int. J. Biol. Macromol. 25, 169–176.
- Iyer, S., Joshi, A., Desai, A. (1997) Rapid detection of a fungal poly(3-hydroxybutyrate) depolymerase using a new in situ gel activity staining technique, Biotechnol. Tech. 11, 905–907.
- Iyer, S., Shah, R., Sharma, A., Jendrossek, D., Desai, A. (2001) Purification of A. fumigatus (Pdf 1) PHB depolymerase using a new, single-step substrate affinity chromatography method: Characterization of the PHB depolymerase exhibiting novel self-aggregation behavior, J. Environ. Polym. Degrad., submitted for publication.
- Jaeger, K. E., Ransac, S., Koch, H. B., Ferrato, F., Dijkstra, B. W. (1993) Topological characterization and modeling of the 3D structure of lipase from Pseudomonas aeruginosa, FEBS Lett. 332, 143–149.
- Jaeger, K.-E., Ransac, S., Dijkstra, B. W., Colson, D., van Heuvel, M., Misset, O. (1994) Bacterial lipases, FEMS Microbiol. Rev. 15, 29–63.
- Jaeger, K.-E., Steinbüchel, A., Jendrossek, D. (1995) Substrate specificities of bacterial polyhydroxyalkanoate depolymerases and lipases: bacterial lipases hydrolyze poly(ω-hydroxyalkanoates), Appl. Environ. Microbiol. 61, 311–318.
- Jaeger, K.-E., Dijkstra, B. W., Reetz, M. T. (1999) Bacterial biocatalysts: molecular biology, three-dimensional structures, and biotechnological applications, Annu. Rev. Microbiol. 53, 315–335.
- Janssen, P. H., Harfoot, C. G. (1990) Ilyobacter delafieldii sp. nov., a metabolically restricted anaerobic bacterium fermenting PHB, Arch. Microbiol. 154, 253–259.
- Janssen, P. H., Schink, B. (1993) Pathway of anaerobic poly-β-hydroxybutyrate degradation by Ilyobacter delafieldii, Biodegradation 4, 179–185.
- Jedlinski, Z., Kurcok, P., Lenz, R. W. (1995) Synthesis of potentially biodegradable polymers, J. Macromol. Sci., Pure Appl. Chem. A32, 797–810.
- Jendrossek, D. (1998) Microbial degradation of polyesters: a review on extracellular poly-(hydroxyalkanoic acid) depolymerases, Polym. Degrad. Stab. 59, 317–325.
- Jendrossek, D. (2001a) Microbial degradation of polyesters, in: Biopolyesters. Advances in biochemical engineering/Biotechnology ( T. Scheper, Ed.), Berlin, Heidelberg: Springer-Verlag, 293–325.
- Jendrossek, D. (2001b) Transfer of [Pseudomonas] lemoignei, a Gram-negative rod with restricted catabolic capacity, to Paucimonas gen. nov. with one species, Paucimonas lemoignei comb. nov., Int. J. Syst. Evol. Microbiol. 51, 905–908.
- Jendrossek, D., Knoke, I., Habibian, R. B., Steinbüchel, A., Schlegel, H. G. (1993a) Degradation of poly(3-hydroxybutyrate), PHB, by bacteria and purification of a novel PHB depolymerase from Comamonas sp., J. Environ. Polym. Degrad. 1, 53–63.
- Jendrossek, D., Müller, B., Schlegel, H. G. (1993b) Cloning and characterization of the poly(hydroxyalkanoic acid)-depolymerase gene locus, phaZ1, of Pseudomonas lemoignei and its gene product, Eur. J. Biochem. 218 701–710.
- Jendrossek, D., Backhaus, M., Andermann, M. (1995a) Characterization of the extracellular poly(3-hydroxy-butyrate) depolymerase of Comamonas sp. and of its structural gene, Can. J. Microbiol. 41 (Suppl. 1), 160–169.
- Jendrossek, D., Frisse, A., Behrends, A., Andermann, M., Kratzin, H. D., Stanislawski, T., Schlegel, H. G. (1995b) Biochemical and molecular characterization of the Pseudomonas lemoignei depolymerase system, J. Bacteriol. 177, 596–607.
- Jendrossek, D., Schirmer, A., Schlegel, H. G. (1996) Biodegradation of polyhydroxyalkanoic acids, Appl. Microbiol. Biotechnol. 46, 451–463.
- Jendrossek, D., Schirmer, A., Handrick, R. (1997) Recent advances in characterization of bacterial PHA depolymerases, in: 1996 International Symposium on bacterial polyhydroxyalkanoates (Eggink, G., Steinbüchel, A., Poirier, Y., Witholt, B., Eds.), Ottawa, Canada: NRC Research Press, 89–101.
- Kanewasa, Y., Tanahashi, N., Doi, Y., Saito, T. (1994) Enzymatic degradation of microbial poly(3-hydroxyalkanoates), Polym. Degrad. Stab. 45, 179–185.
- Kasuya, K., Doi, Y., Yao, T. (1994) Enzymatic degradation of poly[(R)-3-hydroxybutyrate] by Comamonas testosteroni ATSU of soil bacterium, Polym. Degrad. Stab. 45, 379–386.
- Kasuya, K., Inoune, Y., Yamada, K., Doi, Y. (1995) Kinetics of surface hydrolysis of poly[(R)-3-hydroxybutyrate] film by PHB depolymerase from Alcaligenes faecalis T1, Polym. Degrad. Stab. 48, 167–174.
- Kasuya, K., Inoune, Y., Tanaka, T., Akehata, T., Iwata, T., Fukui, T., Doi, Y. (1997) Biochemical and molecular characterization of the polyhydroxybutyrate depolymerase of Comamonas acidovorans YM1609, isolated from freshwater, Appl. Environ. Microbiol. 63, 4844–4852.
- Kasuya, K., Takagi, K., Ishiwatari, S., Yoshida, Y., Doi, Y. (1998) Biodegradabilities of various aliphatic polyesters in natural waters, Polym. Degrad. Stab. 59, 327–332.
- Kasuya, K., Ohura, T., Masuda, K., Doi, Y. (1999) Substrate and binding specificities of bacterial polyhydroxybutyrate depolymerases, Int. J. Biol. Macromol. 24, 329–336.
- Kasuya, K., Nakahara, M., Akiba, A., Kudo, T., Doi, Y. (2000) Identification of a marine benthic P(3HB)-degrading bacterium isolate and characterization of its P(3HB) depolymerase, Biomacromolecules 1, 194–201.
- Kemnitzer, J. E., McCarthy, S. P., Gross, R. A. (1992) Poly(β-hydroxybutyrate) stereoisomers: a model study of the effects of stereochemical and morphological variables on polymer biological degradability, Macromolecules 25, 5927–5934.
-
Kessler, B.,
Witholt, B.
(2001)
Production of microbial polyesters: fermentation and downstream processes, in: Biopolyesters, Advances in Biochemical Engineering/Biotechnology ( T. Scheper, Ed.), Berlin, Heidelberg: Springer-Verlag,
159–182.
10.1007/3-540-40021-4_5 Google Scholar
- Khalmeyer, V., Bornscheuer, U. T. (1999) Overexpression and characterization of an esterase from Streptomyces diastatochromogenes, Biotechnol. Lett. 21, 101–104.
- Kim, H., Park, S.-Y., Lee, J.-K., Oh, T.-K. (1998) Gene cloning and characterization of thermostable lipase from Bacillus stearothermophilus L1., Biosci. Biotechnol. Biochem. 62, 66–71.
- Kim, H., Ju, H.-S., Kim, J. (2000) Characterization of an extracellular poly(3-hydroxy-5-phenylvalerate) depolymerase from Xanthomonas sp. JS02, Appl. Microbiol. Biotechnol. 53, 323–327.
- Kim, J. W., Jung, S. J., Yi, C. O., Ahn, J. S. (2000) , accession no AF293347.
- Kim, Y. B., Lenz, R. W. (2001) Polyesters from microorganisms, in: Biopolyesters. Advances in biochemical engineering/Biotechnology ( T. Scheper, Ed.), Berlin, Heidelberg: Springer-Verlag, 51–80.
- Kita, K., Ishimaru, K., Teraoka, M., Yanase, H., Kato, N. (1995) Properties of poly(3-hydroxybutyrate) depolymerase from a marine bacterium, Alcaligenes eutrophus AE122, Appl. Environ. Microbiol. 61, 1727–1730.
- Kita, K., Mashiba, S., Nagita, M., Ishimaru, K., Okamoto, K., Yanase, H., Kato, N. (1997) Cloning of poly(3-hydroxybutyrate) depolymerase from a marine bacterium, Alcaligenes faecalis AE122, and characterization of its gene product, Biochim. Biophys. Acta 1352, 113–122.
- Klingbeil, B., Kroppenstedt, R., Jendrossek, D. (1996) Taxonomical identification of Streptomyces exfoliatus K10 and characterization of its poly(3-hydroxybutyrate) depolymerase gene, FEMS Microbiol. Lett. 142, 215–221.
- Kobayashi, T., Sugiyama, A., Kawase, Y., Saito, T., Mergaert, J., Swings, J. (1999) Biochemical and genetic characterization of an extracellular poly(3-hydroxybutyrate) depolymerase from Acidovorax sp. strain TP4, Environ. Polym. Degrad. 7, 9–18.
- Kolattukuday, P. E. (2001) Polyesters in higher plants, in: Advances in Biochemical Engineering Biotechnology ( T. Scheper, Ed.), Berlin: Springer-Verlag, 1–50.
- Koyama, N., Doi, Y. (1997) Effect of solid-state structures on the enzymatic degradability of bacterial poly(hydroxyalkanoic acids), Macromolecules 30, 826–832.
- Korherr, C., Roth, M., Holler, E. (1995) Poly(β-l-malate) hydrolase from plasmodia of Physarum polycephalum, Can. J. Microbiol. 41 (Suppl. 1), 192–199.
- Krebsfänger, N., Schierholz, K., Bornscheuer, U. T. (1998) Enantioselectivity of a recombinant esterase from Pseudomonas fluorescens towards alcohols and carboxylic acids, Biotechnology 60, 105–111.
- Kumagai, Y., Kanasawa, Y., Doi, Y. (1992) Enzymatic degradation of microbial poly(3-hydroxybutyrate) films, Makromol. Chem. 193, 53–57.
- Kumar, A., Gross, R. A., Jendrossek, D. (2000) Poly(3-hydroxybutyrate)-depolymerase from Pseudomonas lemoignei: catalysis of esterifications in organic media, J. Org. Chem. 65, 7800–7806.
- Kurcok, P., Kowalczuk, M., Hennek, K., Jedlinski, Z. (1992) Anionic polymerization of β-lactones initiated with alkali-metal alkoxides: reinvestigation of the polymerization mechanism, Macromolecules 2, 2017–2020.
- Kurusu, Y., Kohama, K., Uchida, Y., Saito, T., Yukawa, H. (1994) Cloning and nucleotide sequencing of the poly(3-hydroxybutyrate) depolymerase gene from Pseudomonas pickettii, in: Biodegradable Plastics and Polymers ( Y. Doi, K. Fukuda, Eds.), Elsevier Science BV, 357–361 (see also accession no. D25315).
- Lee, D., Koh, Y., Kim, K., Kim, B., Choi, H., Kim, D., Suhartono, M. T., Pyun, Y. (1999) Isolation and characterization of a thermophilic lipase from Bacillus thermoleovorans ID-1, FEMS Microbiol. Lett. 179, 393–400.
- Lemoigne, M. (1925) Etudes sur l'áutolyse microbienne – Acidification par formation d'ácide β oxbutyrique, Ann. Inst. Pasteur 39, 144–155.
- Lemoigne, M. (1926) Produits de déshydration et de polymerisation de l'ácide β-oxybutyrique, Bull. Soc. Chim. Biol. (Paris) 8, 770–782.
- Lesuisse, E., Schanck, K., Colson, C. (1993) Purification and preliminary characterization of the extracellular lipase of Bacillus subtilis 168, an extremely basic pH-tolerant enzyme, Eur. J. Biochem. 216, 155–160.
- Little, E., Bork, P., Doolittle, R. F. (1994) Tracing the spread of fibronectin type III domains in bacterial glycohydrolases, J. Mol. Evol. 39, 631–643.
- Liu, S., Steinbüchel, A. (1996) Investigation of poly(β-l-malic acid) production by strains of Aureobasidium pullulans, Appl. Microbiol. Biotechnol. 46, 273–278.
- Lundgren, D. G., Pfister, R. M., Merrick, J. M. (1965) Structure of poly-β-hydroxybutyric acid granules, J. Gen. Microbiol. 34, 441–446.
- Lusty, C. J., Doudoroff, M. (1966) Poly-β-hydroxybutyrate depolymerases of Pseudomonas lemoignei, Proc. Natl. Acad. Sci. USA 56, 960–965.
- Madison, L. L., Huisman, G. W. (1999) Metabolic engineering of poly(3-hydroxyalkanoates): from DNA to plastic, Microbiol. Mol. Biol. Rev. 63, 21–53.
- Manco, G., Adinolfi, E., Pisani, F. M., Ottolina, G., Carrea, G., Rossi, M. (1998) Overexpression and properties of a new thermophilic and thermostable esterase from Bacillus acidocaldarius with sequence similarity to hormone-sensitive lipase superfamily, Biochem. J. 332, 203–212.
- Marchessault, R. H. (1996) Tender morsels for bacteria, Trends Polym. Sci. 4, 163–168.
- Marchessault, R. H., Morin, F. G., Wong, S., Saracovan, I. (1995) Artificial granule suspensions of long side chain poly(3-hydroxyalkanoate), Can. J. Microbiol. 41 (Suppl. 1), 138–142.
- Martinez, C., de Geus, P., Lauwereys, M., Matthyssens, G., Cambillau, C. (1992) Fusarium solani cutinase is a lipolytic enzyme with a catalytic serine accessible to solvent, Nature 356, 615–618.
- Matavulj, M., Molitoris, H. P. (1992) Fungal degradation of polyhydroxyalkanoates and a semiquantitative assay for screening their degradation by terrestrial fungi, FEMS Microbiol. Rev. 103, 323–332.
- Mayer, F., Madkour, M. H., Pieper-Fürst, U., Wieczorek, R., Liebergesell, M., Steinbüchel, A. (1996) Electron microscopic observations on the macromolecular organization of the boundary layer of bacterial PHA inclusion bodies, J. Gen. Appl. Microbiol. 42, 445–455.
- McLellan, D. W., Halling, P. J. (1988) Acid-tolerant poly(3-hydroxybutyrate) hydrolase from moulds, FEMS Microbiol. Lett. 52, 215–218.
- Mergaert, J., Webb, A., Anderson, C., Wouters, A., Swings, J. (1993) Microbial degradation of poly(3-hydroxy-butyrate) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) in soils, Appl. Environ. Microbiol. 59, 3233–3238.
- Mergaert, J., Webb, A., Anderson, C., Wouters, A., Swings, J. (1994) Microbial degradation of poly(3-hydroxy-butyrate) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) in compost, J. Environ. Polym. Degrad. 2, 177–183.
- Mergaert, J., Wouters, A., Anderson, C., Swings, J. (1995) In situ biodegradation of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) in natural waters, Can. J. Microbiol. 41 (Suppl. 1), 154–159.
- Mergaert, J., Glorieux, G., Hauben, L., Storms, V., Mau, M., Swings, J. (1996a) Biodegradation of poly(3-hydroxyalkanoates) in anaerobic sewage sludge and characterization of a poly(3-hydroxyalkanoates) degrading anaerobic bacterium, Syst. Appl. Microbiol. 19, 407–413.
- Mergaert, J., Schirmer, A., Hauben, L., Mau, M., Jendrossek, D., Swings, J. (1996b) Isolation and identification of poly(3-hydroxyvalerate) degrading strains of Pseudomonas lemoignei, Int. J. Syst. Bacteriol. 46, 769–773.
- Merrick, J. M., Doudoroff, M. (1964) Depolymerisation of poly-β-hydroxybutyrate by an intracellular enzyme system, J. Bacteriol. 88, 60–71.
- Merrick, J. M., Yu, C. I. (1966) Purification and properties of a d(-)-β-hydroxybutyric dimer hydrolase from Rhodospirillum rubrum, Biochemistry 5, 3563–3568.
- Merrick, J. M., Lundgren, D. G., Pfister, R. M. (1965) Morphological changes in poly-β-hydroxybutyrate granules associated with decreased susceptibility to enzymatic hydrolysis, J. Bacteriol. 89, 234–239.
- Merrick, J. M., Steger, R., Dombroski, D. (1999) Hydrolysis of native poly(hydroxybutyrate) granules (PHB), crystalline PHB, and artificial amorphous PHB granules by intracellular and extracellular depolymerases, Int. J. Biol. Macromol. 25, 129–134.
- Molitoris, K. P., Moss, S. T., de Koning, G., Jendrossek, D. (1996) SEM analysis of poly-hydroxyalkanoate degradation by bacteria, Appl. Microbiol. Biotechnol. 46, 570–579.
- Müller, B., Jendrossek, D. (1993) Purification and properties of a poly(3-hydroxyvalerate) depolymerase from Pseudomonas lemoignei, Appl. Microbiol. Biotechnol. 38, 487–492.
- Müller, H. M., Seebach, D. (1993) Poly(hydroxyalkanoates): a fifth class of physiologically important organic biopolymers? Angew. Chem. Int. Edn. Engl. 32, 477–502.
- Mukai, K., Doi, Y., Sema, Y., Tomita, K. (1993a) Substrate specificities in hydrolysis of polyhydroxyalkanoates by microbial esterases, Biotechnol. Lett. 15, 601–604.
- Mukai, K., Yamada, K., Doi, Y. (1993b) Enzymatic degradation of poly(hydroxyalkanoates) by a marine bacterium, Polym. Degrad. Stab. 41, 85–91.
- Mukai, K., Yamada, K., Doi, Y. (1994) Efficient hydrolysis of polyhydroxyalkanoates by Pseudomonas stutzeri YM1414 isolated from lake water, Polym. Degrad. Stab. 43, 319–327.
- Murphey, C. A., Cameron, J. A., Huang, S. J., Vinopal, R. T. (1996) Fusarium polycaprolactone depolymerase is cutinase, Appl. Environ. Microbiol. 62, 456–460.
- Nakayama, K., Saito, T., Fukui, T., Shirakura, Y., Tomita, K. (1985) Purification and properties of extracellular poly(3-hydroxybutyrate) depolymerases from Pseudomonas lemoignei, Biochim. Biophys. Acta 827, 63–72.
- Neumeier, S. (1994) Abbau thermoplastischer Biopolymere auf Poly-β-Hydroxyalkanoat-Basis durch terrestrische und marine Pilze, Diploma Thesis, Universität Regensburg, Germany.
- Nishida, H., Tokiwa, Y. (1993) Effects of high-order structure of poly(3-hydroxybutyrate) on its biodegradation. II. Effects of crystal structure on microbial degradation, J. Environ. Polym. Degrad. 1, 65–80.
- Nobes, G. A. R., Marchessault, R. H., Chanzy, H., Briese, B. H., Jendrossek, D. (1996) Splintering of poly(3-hydroxybutyrate) single crystals by PHB-depolymerase A from Pseudomonas lemoignei, Macromolecules 29, 8330–8333.
- Nobes, G. A. R., Marchessault, R. H., Briese, B. H., Jendrossek, D. (1998) Microscopic visualization of the enzymatic degradation of poly(3HB-co-3HV) and poly(3HV) single crystals by PHA depolymerases from Pseudomonas lemoignei, J. Environ. Polym. Degrad. 5, 99–107.
- Nojiri, M., Saito, T. (1997) Structure and function of poly(3-hydroxybutyrate) depolymerases from Alcaligenes faecalis T1, J. Bacteriol. 179, 6965–6970.
- Nomura, N., Shigeno-Akutsu, Y., Nakajima-Kambe, T., Nakahara, T. (1998) Cloning and sequence analysis of a polyurethane-esterase of Comamonas acidovorans TB-35, J. Ferment. Bioeng. 86, 339–345.
- Oda, Y., Oida, N., Urakami, T., Tonomura, K. (1997a) Polycaprolactone depolymerase produced by the bacterium Alcaligenes faecalis, FEMS Microbiol. Lett. 152, 339–343.
- Oda, Y., Osaka, H., Urakami, T., Tonomura, K. (1997b) Purification and properties of poly(3-hydroxybutyrate) depolymerase from the fungus Paecilomyces lilacinus D218, Curr. Microbiol. 34, 230–232.
- Ohura, T., Aoyagi, Y., Takagi, K., Yoshida, Y., Kasuya, K., Doi, Y. (1999a) Biodegradation of poly(3-hydroxyalkanoic acids) fibers and isolation of poly(3-hydroxybutyric acid)-degrading microorganisms under aquatic environments, Polym. Degrad. Stab. 63, 23–29.
- Ohura, T., Kasuya, K., Doi, Y. (1999b) Cloning and characterization of the polyhydroxybutyrate depolymerase gene of Pseudomonas stutzeri and analysis of the function of substrate-binding domains, Appl. Environ. Microbiol. 65, 189–197.
- Ollis, D. L., Cheah, E., Cygler, M., Dijkstra, B., Frolow, F., Franken, S. M., Harel, M., Remington, S. J., Silman, I., Schrag, J., Sussmann, J. L., Verschueren, K. H. G., Goldman, A. (1992) The α/β hydrolase fold, Protein Eng. 5, 197–211.
- Pranamuta, H., Tokiwa, Y., Tanaka, H. (1997) Polylactide degradation by an Amycolatopsis sp., Appl. Environ. Microbiol. 63, 1637–1640.
- Quinteros, R., Goodwin, S., Lenz, R. W., Park, W. H. (1999) . Extracellular degradation of medium chain length poly(beta-hydroxyalkanoates) by Comamonas sp., Int. J. Biol. Macromol. 25, 135–143.
- Ramsay, B. A., Saracovan, I., Ramsay, J. A., Marchessault, R. H. (1994) A method for the isolation of microorganisms producing extracellular long-side-chain poly(β-hydroxyalkanoate) depolymerase, J. Environ. Polym. Degrad. 2, 1–7.
- Ruiz, J. A., Lopez, N. I., Fernandez, R. O., Mendez, B. S. (2001) Polyhydroxyalkanoate degradation is associated with nucleotide accumulation and enhances stress resistance and survival of Pseudomonas oleovorans in natural water microcosms, Appl. Environ. Microbiol. 67, 225–230.
- Sadocco, P., Nocerino, S., Dubini-Paglia, E., Seves, A., Elegir, G. (1997) Characterization of a poly(3-hydroxybutyrate) depolymerase from Aureobacterium saperdae: active site studies and kinetics of hydrolysis studies, J. Environ. Polym. Degrad. 5, 57–65.
- Saegusa, H., Shiraki, M., Kanai, C., Saito, T. (2001) Cloning of an intracellular poly[d(-)-3-hydroxybutyrate] depolymerase gene from Ralstonia eutropha H16 and characterization of the gene product, J. Bacteriol. 183, 94–100.
- Saito, T., Suzuki, K., Yamamoto, J., Fukui, T., Miwa, K., Tomita, K., Nakanishi, S., Odani, S., Suzuki, J. I., Ishikawa, K. (1989) Cloning, nucleotide sequence, and expression in Escherichia coli of the gene for poly(3-hydroxy-butyrate) depolymerase from Alcaligenes faecalis, J. Bacteriol. 171, 184–189.
- Saito, T., Saegusa, H., Miyata, Y., Fukui, T. (1992) Intracellular degradation of poly(3-hydroxybutyrate) granules of Zoogloea ramigera I-16-M, FEMS Microbiol. Rev. 103, 333–338.
- Saito, T., Takizawa, K., Saegusa, H. (1995) Intracellular poly(3-hydroxybutyrate) depolymerase in Alcaligenes eutrophus, Can. J. Microbiol. 41 (Suppl. 1), 187–191.
- Saito, T. (1999) accession no J04223.
- Sasikala, C., Ramana, C. V. (1996) Biodegradable polyesters, Adv. Appl. Microbiol. 42, 97–218.
- Scandola, M. (1997) Blends of natural and synthetic PHAs, in: 1996 International Symposium on Bacterial Polyhydroxyalkanoates ( G. Eggink, A. Steinbüchel, Y. Poirier, B. Witholt, Eds.), Ottawa, Canada: NRC Research Press, 20–27.
- Scandola, M., Pizzoli, M., Ceccorulli, G., Cesaro, A., Paoletti, S., Navarini, L. (1988) Viscoelastic and thermal properties of bacterial poly(d-(−)-β-hydroxybutyrate), Int. J. Biol. Macromol. 10, 373–377.
- Scandola, M., Focarete, M. L., Adamus, G., Sikorska, W., Baranowska, I., Swierczek, S., Gnatowski, M., Kowalczuk, M., Jedlinski, Z. (1997a) Polymer blends of natural poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and synthetic atactic poly(3-hydroxybutyrate). Characterization and biodegradation studies, Macromolecules 30, 2568–2574.
- Scandola, M., Focarete, M. L., Gazzano, M., Matuszowicz, A., Sikorska, W., Adamus, G., Kurcok, P., Kowalczuk, M., Jedlinski, Z. (1997b) Crystallinity-induced biodegradation of novel [(R,S)-β-butyrolactone]-β-pivalactone copolymers, Macromolecules 30, 7743–7748.
- Scandola, M., Focarete, M. L., Frisoni, G. (1998) Simple kinetic model for the heterogeneous enzymatic hydrolysis of natural poly(3-hydroxybutyrate), Macromolecules 31, 3846–3851.
- Scherer, T. M., Fuller, C., Goodwin, S., Lenz, R. W. (2000) Enzymatic hydrolysis of oligomeric models of poly-3-hydroxybutyrate, Biomacromolecules 1, 577–583.
- Schirmer, A., Jendrossek, D. (1994) Molecular characterization of the extracellular poly(3-hydroxyoctanoic acid) [P(3HO)] depolymerase gene of Pseudomonas fluorescens GK13 and of its gene product, J. Bacteriol. 176, 7065–7073.
- Schirmer, A., Jendrossek, D., Schlegel, H. G. (1993) Degradation of poly(3-hydroxyoctanoic acid), [P(3HO)], by bacteria. Purification and properties of a P(3HO) depolymerase of Pseudomonas fluorescens GK13 biovarV, Appl. Environ. Microbiol. 59, 1220–1227.
- Schirmer, A., Matz, C., Jendrossek, D. (1995) Substrate specificities of PHA-degrading bacteria and active site studies on the extracellular poly(3-hydroxyoctanoic acid) [P(3HO)] depolymerase of Pseudomonas fluorescens GK13, Can. J. Microbiol. 41 (Suppl. 1), 170–179.
- Schmidt-Dannert, C., Rúa, M. L., Atomi, H., Schmid, R. D. (1996) Thermoalkalophilic lipase of Bacillus thermocatenulatus. I. Molecular cloning, nucleotide sequence, purification and some properties, Biochim. Biophys. Acta 1301, 105–114.
- Schöber, U., Thiel, C., Jendrossek, D. (2000) Poly(3-hydroxyvalerate) depolymerase of Pseudomonas lemoignei, Appl. Environ. Microbiol. 66, 1385–1392.
- Sharma, R., Ray, A. R. (1995) Polyhydroxybutyrate, its copolymers and blends, J. Mater. Sci.: Rev. Macromol. Phys. C35, 327–359.
- Shinohe, T., Nojiri, M., Saito, T., Stanislawski, T., Jendrossek, D. (1996) Determination of the active sites serine of the poly(3-hydroxybutyrate) depolymerases of Pseudomonas lemoignei (PhaZ5) and of Alcaligenes faecalis, FEMS Microbiol. Lett. 141, 103–109.
- Shinomiya, M., Iwata, T., Kasuya, K., Doi, Y. (1997) Cloning of the gene for poly(3-hydroxybutyric acid) depolymerase of Comamonas testosteroni and functional analysis of its substrate-binding domain, FEMS Microbiol. Lett. 154, 89–94.
- Shiraki, M., Shimada, T., Tatsumichi, M., Saito, T. (1995) Purification and characterization of extracellular poly(3-hydroxybutyrate) depolymerases, J. Environ. Polym. Degrad. 3, 13–21.
- Shirakura, Y., Fukui, T., Tanio, T., Nakayama, K., Matsuno, R., Tomita, K. (1983) An extracellular d(-)-3-hydroxybutyrate oligomer hydrolase from Alcaligenes faecalis, Biochim. Biophys. Acta 748, 331–339.
- Shirakura, Y., Fukui, T., Saito, T., Okamoto, Y., Narikawa, T., Koide, K., Tomita, K., Takemasa, T., Masamune, S. (1986) Degradation of poly(3-hydroxybutyrate) depolymerase from Alcaligenes faecalis T1, Biochim. Biophys. Acta 880, 46–53.
- Soliday, C. L., Flurkey, W. H., Okita, T. W., Kolattukuday, P. E. (1984) Cloning and structure determination of cDNA for cutinase, an enzyme involved in fungal penetration of plants, Proc. Natl. Acad. Sci. USA 81, 3939–3943.
- Spiekermann, P., Rehm, B. H. A., Kalscheuer, R., Baumeister, D., Steinbüchel, A. (1999) A sensitive viable-colony staining method using Nile red for direct screening of bacteria that accumulate polyhydroxyalkanoic acids and other lipid storage compounds, Arch. Microbiol. 171, 73–80.
- Spyros, A., Kimmich, R., Briese, B. H., Jendrossek, D. (1997) 1H NMR imaging study of enzymatic degradation in poly(3-hydroxybutyrate) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate), Macromolecules 30, 8218–8225.
- Steinbüchel, A. (1991) Polyhydroxyalkanoic acids, in: Biomaterials ( B. Byrom, Ed.), Basingstoke: Macmillan Publishers Ltd., 122–213.
- Steinbüchel, A., Fürchtenbusch, B. (1998) Bacterial and other biological systems for polyester production, Trends Biotechnol. 16, 419–426.
-
Steinbüchel, A..,
Hein, S.
(2001)
Biochemical and molecular basis of microbial synthesis of polyhydroxyalkanoates in microorganisms, in: Biopolyesters, Advances in Biochemical Engineering/Biotechnology ( T. Scheper, Ed.), Berlin, Heidelberg: Springer-Verlag,
81–124.
10.1007/3-540-40021-4_3 Google Scholar
- Steinbüchel, A., Valentin, H. E. (1995) Diversity of bacterial polyhydroxyalkanoic acids, FEMS Microbiol. Lett. 128, 219–228.
- Steinbüchel, A., Aerts, K., Babel, W., Föllner, C., Liebergesell, M., Madkour, M. H., Mayer, F., Pieper-Fürst, U., Pries, A., Valentin, H. E., Wieczorek, R. (1995) Considerations on the structure and biochemistry of bacterial polyhydroxyalkanoic acids inclusions, Can. J. Microbiol. 41 (Suppl. 1), 94–105.
- Stinson, M. W., Merrick, J. M. (1974) Extracellular enzyme secretion by Pseudomonas lemoignei, J. Bacteriol. 119, 152–161.
- Stuer, W., Jaeger, K.-E., Winkler, U. K. (1986) Purification of extracellular lipase from Pseudomonas aeruginosa, J. Bacteriol. 168, 1070–1074.
- Svendsen, A., Borch, K., Barfoed, M., Nielsen, T. B., Gormsen, E., Patkar, S. A. (1995) Biochemical properties of cloned lipase from the Pseudomonas family, Biochim. Biophys. Acta 1259, 9–17.
- Takeda, M., Kitashima, K., Adachi, K., Hanaoka, Y., Suzuki, I., Koizumi, J. (2000) Cloning and expression of the gene encoding thermostable poly(3-hydroxybutyrate) depolymerase, J. Biosci. Bioeng. 90, 416–421.
- Tanaka, Y., Saito, T., Fukui, T., Tanio, T., Tomita, K. (1981) Purification and properties of d-(−)-3-hydroxybutyrate dimer hydrolase from Zoogloea ramigera I-16-M, Eur. J. Biochem. 118, 177–182.
- Tanio, T., Fukui, T., Shirakura, Y., Saito, T., Tomita, K., Kaiho, T. (1982) An extracellular poly(3-hydroxybutyrate) depolymerase from Alcaligenes faecalis, Eur. J. Biochem. 124, 71–77.
- Terpe, K., Kerkhoff, K., Pluta, E., Jendrossek, D. (1999) Relationship between succinate transport and production of extracellular poly(3-hydroxybutyrate) depolymerase in Pseudomonas lemoignei, Appl. Environ. Microbiol. 65, 1703–1709.
- Tomasi, G., Scandola, M., Briese, B.-H., Jendrossek, D. (1996) Enzymatic degradation of bacterial poly(3-hydroxybutyrate) by a depolymerase from Pseudomonas lemoigeni, Macromolecules 29, 507–513.
- Uefuji, M., Kasuya, K., Doi, Y. (1997) Enzymatic degradation of poly[(R)-3-hydroxybutyrate]: secretion and properties of PHB depolymerase from Pseudomonas stutzeri, Polym. Degrad. Stab. 58, 275–281.
- Watanabe, T., Ito, Y., Yamada, T., Hashimoto, M., Sekine, S., Tanaka, H. (1994) The roles of the C-terminal domain and type III domains of chitinases A1 from Bacillus circulans WL-12 in chitin degradation, J. Bacteriol. 176, 4465–4472.
- Wilde, E. (1962) Untersuchungen über Wachstum und Speicherstoffsynthese von Hydrogenomonas, Arch. Mikrobiol. 43, 109–137.
- Wu, K., Chung, L., Revill, W. P., Katz, L., Reeves, C. D. (2000) The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units, Gene 251, 81–90.
- Yabuchi, E., Kosako, Y., Yano, I., Hotta, H., Nishiuchi, Y. (1995) Transfer of two Burkholderia and an Alcaligenes species to Ralstonia gen. nov.: proposal of Ralstonia pickettii (Ralston, Palleroni, Doudoroff 1973) comb. nov. Ralstonia solanacearum (Smith 1896) comb. nov. and Ralstonia eutropha (Davis 1969) comb. nov., Microbiol. Immunol. 39, 897–904.
- Yamada, K., Mukai, K., Doi, Y. (1993) Enzymatic degradation of poly(hydroxyalkanoates) by Pseudomonas pickettii, Int. J. Biol. Macromol. 15, 215–220.
- Yoon, S. C., Choi, M. H. (1999) Local sequence dependence of polyhydroxyalkanoic acid degradation in Hydrogenophaga pseudoflava, J. Biol. Chem. 274, 37800–37808.
- Zhang, K., Shiraki, M., Saito, T. (1997) Purification of an extracellular d-(-)-3-hydroxybutyrate oligomer hydrolase from Pseudomonas sp. strain A1 and cloning and sequencing of its gene, J. Bacteriol. 179, 72–77.
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