Metabolic Pathways and Engineering of Polyhydroxyalkanoate Biosynthesis

Part 3a. Polyesters
Dr. Kazunori Taguchi

Dr. Kazunori Taguchi

Polymer Chemistry Laboratory, RIKEN Institute, Hirosawa 2-1, Wako-shi, Saitama, Japan, 351-0198

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Dr. Seiichi Taguchi

Dr. Seiichi Taguchi

Polymer Chemistry Laboratory, RIKEN Institute, Hirosawa 2-1, Wako-shi, Saitama, Japan, 351-0198

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Dr. Kumar Sudesh

Dr. Kumar Sudesh

Polymer Chemistry Laboratory, RIKEN Institute, Hirosawa 2-1, Wako-shi, Saitama, Japan, 351-0198

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Dr. Akira Maehara

Dr. Akira Maehara

Polymer Chemistry Laboratory, RIKEN Institute, Hirosawa 2-1, Wako-shi, Saitama, Japan, 351-0198

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Dr. Takeharu Tsuge

Dr. Takeharu Tsuge

Polymer Chemistry Laboratory, RIKEN Institute, Hirosawa 2-1, Wako-shi, Saitama, Japan, 351-0198

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Prof. Dr. Yoshiharu Doi

Prof. Dr. Yoshiharu Doi

Polymer Chemistry Laboratory, RIKEN Institute, Hirosawa 2-1, Wako-shi, Saitama, Japan, 351-0198

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First published: 15 January 2005
Citations: 8

Abstract

  • Introduction
  • Metabolic Pathways for PHA Biosynthesis
  • Organization of the Genes Involved in PHA Biosynthesis
  • Monomer-supplying Enzymes for PHA Biosynthesis
    • β-Ketothiolase (PhaA)
    • Acetoacetyl-CoA Reductase (PhaB)
    • (R)-3-Hydroxyacyl-ACP–CoA transferase (PhaG)
    • (R)-Specific Enoyl-CoA Hydratase (PhaJ)
  • Metabolic Engineering and Improvements in PHA Biosynthesis
    • Metabolic Engineering for PHA Production in Recombinant Escherichia coli
    • Metabolic Improvement for PHA Production in Ralstonia eutropha PHB-4 and Pseudomonads
  • Outlook and Perspectives

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