Acid–Base Catalysis – Biological
A. Williams,
A. Williams
Chemical Laboratory, University of Kent, Canterbury, Kent, England, United Kingdom
Search for more papers by this authorA. Williams,
A. Williams
Chemical Laboratory, University of Kent, Canterbury, Kent, England, United Kingdom
Search for more papers by this authorFirst published: 15 July 2002
Abstract
Acid–base catalysis, the process where the transfer of a proton facilitates a reaction, is shown to play an important catalytic role across a wide range of organic and bioorganic reactions. The origins of the catalytic advantage of acid–base catalysis are described and the concepts are illustrated with examples taken form a spectrum of fields from synthetic organic chemistry to enzyme action.
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