Diagnostic Test Evaluation without a Gold Standard

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G. H. De Bock

G. H. De Bock

Leiden University, Leiden, The Netherlands

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J. C. Van Houwelingen

J. C. Van Houwelingen

Leiden University, Leiden, The Netherlands

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First published: 15 July 2005

Abstract

In case of unknown sensitivity and specificity of a reference test, the sensitivity and specificity of a diagnostic test can be estimated by the EM algorithm.

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