Communication
Bioaffinity NMR Spectroscopy: Identification of an E-Selectin Antagonist in a Substance Mixture by Transfer NOE
First published: 04 February 2004
Citations: 59
Abstract
Unambiguous identification of the E-selectin antagonist 1 in a mixture of potential E-selectin ligands is possible with a bioactivity assay that is based on transfer NOE. This is remarkable, since the compounds present in the mixture have similar structures and their 1H NMR signals overlap extensively.
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