Volume 10, Issue 3 pp. 223-230
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C-phosphorylation of 2,5-dimethyl-N-arylpyrroles

Andrei A. Tolmachev

Corresponding Author

Andrei A. Tolmachev

Institute of Organic Chemistry of the National Academy of Sciences of Ukraine, Murmanskaya Str. 5, Kiev-94, 253660, Ukraine

Institute of Organic Chemistry of the National Academy of Sciences of Ukraine, Murmanskaya Str. 5, Kiev-94, 253660, UkraineSearch for more papers by this author
Sergei P. Ivonin

Sergei P. Ivonin

Institute of Organic Chemistry of the National Academy of Sciences of Ukraine, Murmanskaya Str. 5, Kiev-94, 253660, Ukraine

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Alksandra A. Chaikovshaya

Alksandra A. Chaikovshaya

Institute of Organic Chemistry of the National Academy of Sciences of Ukraine, Murmanskaya Str. 5, Kiev-94, 253660, Ukraine

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Tatiana E. Terikovska

Tatiana E. Terikovska

Institute of Organic Chemistry of the National Academy of Sciences of Ukraine, Murmanskaya Str. 5, Kiev-94, 253660, Ukraine

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Tamara N. Kudrya

Tamara N. Kudrya

Institute of Organic Chemistry of the National Academy of Sciences of Ukraine, Murmanskaya Str. 5, Kiev-94, 253660, Ukraine

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Aleksandr M. Pinchuk

Aleksandr M. Pinchuk

Institute of Organic Chemistry of the National Academy of Sciences of Ukraine, Murmanskaya Str. 5, Kiev-94, 253660, Ukraine

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Abstract

C-Phosphorylation of 2,5-dimethylpyrroles with phosphorus (III) halides has been studied. Synthetic methods have been elaborated that provide an access to 3-phosphorylated 2,5-dimethylpyrroles, including pyrrole-substituted halogeno and dihalogeno phosphines; on this basis, a variety of trivalent and pentavalent phosphorus derivatives has been obtained. Ortho-diphosphorylated 2,5-dimethyl-N-arylpyrrole derivatives have been synthesized for the first time. © 1999 John Wiley & Sons, Inc. Heteroatom Chem 10:223–230, 1999

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