Root stimulation improves the detection of acquired demyelinating polyneuropathies
Corresponding Author
Daniel L. Menkes MD
Department of Neurology, University of Louisville, 500 South Preston Street, Louisville, Kentucky 40292, USA
Department of Neurology, University of Louisville, 500 South Preston Street, Louisville, Kentucky 40292,USASearch for more papers by this authorDaniel C. Hood MD
Section of Neurology, Department of Medicine, 60th MDOS/SGOMU, David Grant USAF Medical Center, 101 Bodin Circle, Travis AFB California 94535-5300, USA
Search for more papers by this authorRoderick A. Ballesteros R EDT
Section of Neurology, Department of Medicine, 60th MDOS/SGOMU, David Grant USAF Medical Center, 101 Bodin Circle, Travis AFB California 94535-5300, USA
Search for more papers by this authorDavid A. Williams MD
Section of Neurology, Department of Medicine, 60th MDOS/SGOMU, David Grant USAF Medical Center, 101 Bodin Circle, Travis AFB California 94535-5300, USA
Search for more papers by this authorCorresponding Author
Daniel L. Menkes MD
Department of Neurology, University of Louisville, 500 South Preston Street, Louisville, Kentucky 40292, USA
Department of Neurology, University of Louisville, 500 South Preston Street, Louisville, Kentucky 40292,USASearch for more papers by this authorDaniel C. Hood MD
Section of Neurology, Department of Medicine, 60th MDOS/SGOMU, David Grant USAF Medical Center, 101 Bodin Circle, Travis AFB California 94535-5300, USA
Search for more papers by this authorRoderick A. Ballesteros R EDT
Section of Neurology, Department of Medicine, 60th MDOS/SGOMU, David Grant USAF Medical Center, 101 Bodin Circle, Travis AFB California 94535-5300, USA
Search for more papers by this authorDavid A. Williams MD
Section of Neurology, Department of Medicine, 60th MDOS/SGOMU, David Grant USAF Medical Center, 101 Bodin Circle, Travis AFB California 94535-5300, USA
Search for more papers by this authorAbstract
Thirty-one patients with a presentation compatible with an acquired demyelinating polyradiculoneuropathy were prospectively e avaluated for proximal conduction block using root stimulation (RS) of cervical and/or lumbar roots. These same techniques were applied to 78 controls (40 pathological). Proximal conduction block was noted in 20/31 cases and none of the controls. Only 7 of 31 cases met published demyelinating criteria. Intravenous immune globulin therapy was completed by 21/31 patients and 20/21 responded. RS is superior to published electrophysiologic criteria for identifying demyelinating polyneuropathies and predicting who will respond to treatment. RS should be performed in all patients suspected of having an acquired demyelinating polyneuropathy when traditional nerve conduction studies criteria are nondiagnostic. RS reliably predicts those likely to respond to immunosuppressive therapy. © 1998 John Wiley & Sons, Inc. Muscle Nerve 21:298–308, 1998.
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