Absence of intragenic mismatch mutations in small cell lung cancers with microsatellite instability
Ramaswamy Anbazhagan
Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Search for more papers by this authorAdrian Merlo
Department of Molecular Neuro-Oncology Research, University Hospital, Basel, Switzerland
Search for more papers by this authorDavid Sidransky
Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Department of Otolaryngology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Search for more papers by this authorCorresponding Author
Edward Gabrielson
Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, Baltimore, MD 21224–2780, USA. Fax: (410)550–0316.Search for more papers by this authorRamaswamy Anbazhagan
Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Search for more papers by this authorAdrian Merlo
Department of Molecular Neuro-Oncology Research, University Hospital, Basel, Switzerland
Search for more papers by this authorDavid Sidransky
Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Department of Otolaryngology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Search for more papers by this authorCorresponding Author
Edward Gabrielson
Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, Baltimore, MD 21224–2780, USA. Fax: (410)550–0316.Search for more papers by this author
REFERENCES
- Abe, T., Ouyang, H., Migita, T., Kato, Y., Kimura, M., Shiiba, K., Sunamura, M., Matsuno, S., and Horii, A., The somatic mutation frequency of the transforming growth factor beta receptor type II gene varies widely among different cancers with microsatellite instability. Europ. J. Surg. Oncol., 22, 474–477 (1996). Medline
- Mao, L., Lee, D.J., Tockman, M.S., Erozan, Y.S., Askin, F., and Sidransky, D., Microsatellite alterations as clonal markers for the detection of human cancer. Proc. nat. Acad. Sci. (Wash.), 91, 9871–9875 (1994).
- Merlo, A., Mabry, M., Gabrielson, E., Vollmer, R., Baylin, S.B., and Sidransky, D., Frequent microsatellite instability in primary small cell lung cancer. Cancer Res, 54, 2098–2101 (1994). Medline
- Myeroff, L.L., and 16 others, A transforming growth factor beta receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability. Cancer Res., 55, 5545–5547 (1995). Medline
- Parsons, R., Myeroff, L.L., Liu, B., Willson, J.K., Markowitz, S.D., Kinzler, K.W., and Vogelstein, B., Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer. Cancer Res, 55, 5548–5550 (1995). Medline
- Rampino, N., Yamamoto, H., Ionov, Y., Li, Y., Sawai, H., Reed, J.C., and Perucho, M., Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science, 275, 967–969 (1997). Medline
- Ryberg, D., Lindstedt, B.A., Zienolddiny, S., and Haugen, A., A hereditary genetic marker closely associated with microsatellite instability in lung cancer. Cancer Res, 55, 3996–3999 (1995). Medline
- Souza, R.F., and 20 others, Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours. Nature (Genet.), 14, 255–257 (1996). Medline
- Souza, R.F., and 20 others, Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumors. Cancer Res., 57, 2350–2353 (1997). Medline
- Speicher, M.R., Microsatellite instability in human cancer. Oncol. Res, 7, 267–275 (1995). Medline
- Takenoshita, S., Hagiwara, K., Gemma, A., Nagashima, M., Ryberg, D., Lindstedt, B., Bennett, W.P., Haugen, A., and Harris, C.C., Absence of mutations in the transforming growth factor-beta type II receptor in sporadic lung cancers with microsatellite instability and rare H-ras1 alleles. Carcinogenesis, 18, 1427–1429 (1997). Medline