Factors Affecting Emergency Department Opioid Administration to Severely Injured Patients
Corresponding Author
Martha L. Neighbor MD
Department of Medicine (MLN), School of Medicine (SH), and Department of Epidemiology and Biostatistics (MAK), University of California, San Francisco, San Francisco, CA
San Francisco General Hospital Emergency Services (MLN), San Francisco, CA.
Emergency Services 1E21, San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110. Fax: 415-206-5818;; e-mail: [email protected]Search for more papers by this authorSamantha Honner MD
Department of Medicine (MLN), School of Medicine (SH), and Department of Epidemiology and Biostatistics (MAK), University of California, San Francisco, San Francisco, CA
Search for more papers by this authorMichael A. Kohn MD, MPP
Department of Medicine (MLN), School of Medicine (SH), and Department of Epidemiology and Biostatistics (MAK), University of California, San Francisco, San Francisco, CA
Search for more papers by this authorCorresponding Author
Martha L. Neighbor MD
Department of Medicine (MLN), School of Medicine (SH), and Department of Epidemiology and Biostatistics (MAK), University of California, San Francisco, San Francisco, CA
San Francisco General Hospital Emergency Services (MLN), San Francisco, CA.
Emergency Services 1E21, San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110. Fax: 415-206-5818;; e-mail: [email protected]Search for more papers by this authorSamantha Honner MD
Department of Medicine (MLN), School of Medicine (SH), and Department of Epidemiology and Biostatistics (MAK), University of California, San Francisco, San Francisco, CA
Search for more papers by this authorMichael A. Kohn MD, MPP
Department of Medicine (MLN), School of Medicine (SH), and Department of Epidemiology and Biostatistics (MAK), University of California, San Francisco, San Francisco, CA
Search for more papers by this authorAbstract
Objectives: Studies of emergency department (ED) pain management in patients with trauma have been mostly restricted to patients with fractures, yet the potential for undertreatment of more severely injured patients is great. The authors sought to identify factors associated with failure to receive ED opioid administration in patients with acute trauma who subsequently required hospitalization. Methods: At an urban Level 1 trauma center and teaching hospital, a retrospective cohort study of trauma team activation patients requiring hospitalization between January 1 and December 31, 1999, was conducted. The authors excluded patients receiving opioids only within ten minutes of chest tube insertion or fracture manipulation. The main outcome measure was ED opioid administration. Results: A total of 540 charts of hospitalized first-tier trauma team activation patients were reviewed. A total of 258 (47.8%) received intravenous opioid analgesia within three hours of ED arrival. The median time to receiving the first dose of opioids was 95 minutes. Patients were independently less likely to receive opioids if they were younger or older, were intubated, had a lower Revised Trauma Score, or did not require fracture manipulation. Patients with these factors were less likely to receive opioids independent of the amount of time they spent in the ED. Conclusions: Many trauma activation patients requiring hospitalization do not receive opioid analgesia in the ED. Patients at particular risk for oligoanalgesia include those who are younger or older and those who are more seriously injured, as defined by a lower Revised Trauma Score, lower Glasgow Coma Scale score, and intubation.
References
- Wilson JE, Pendleton JM. Oligoanalgesia in the emergency department. Am J Emerg Med. 1989; 7: 620–3.
- Selbst SM, Clark M. Analgesic use in the emergency department. Ann Emerg Med. 1990; 19: 1010–3.
- Lewis LM, Lasater LC, Brooks CB. Are emergency physicians too stingy with analgesics? South Med J. 1994; 87: 7–9.
- Friedland LR, Pancioli AM, Duncan KM. Pediatric emergency department analgesic practice. Pediatr Emerg Care. 1997; 13: 103–6.
- Guru V, Dubinsky I. The patient vs. caregiver perception of acute pain in the emergency department. J Emerg Med. 2000; 18: 7–12.
- Ducharme J. Acute pain and pain control: state of the art. Ann Emerg Med. 2000; 35: 592–603.
- Friedland LR, Kulick RM. Emergency department analgesic use in pediatric trauma victims with fractures. Ann Emerg Med. 1994; 23: 203–7.
- Jantos, TJ, Paris, PM, Menegazzi, JJ, Yealy, DM. Analgesic practice for acute orthopedic trauma pain in Costa Rican emergency departments. Ann Emerg Med. 1996; 28: 145–50.
- Petrack EM, Christopher NC, Kriwinsky J. Pain management in the emergency department: patterns of analgesic utilization. Pediatrics. 1997; 99: 711–4.
-
Brown, JC,
Klein, EJ,
Lewis, CW,
Johnston, BD,
Cummings, P.
Emergency department analgesia for fracture pain.
Ann Emerg Med.
2003; 42: 197–205.
10.1067/mem.2003.275 Google Scholar
- Todd KH, Samaroo N, Hoffman JR. Ethnicity as a risk factor for inadequate emergency department analgesia. JAMA. 1993; 269: 1537–9.
- Todd, KH, Deaton, C, D'Adamo, AP, Goe, L. Ethnicity and analgesic practice. Ann Emerg Med. 2000; 35: 11–6.
- Hostetler MA, Auinger P, Szilagyi PG. Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMS) 1992-1997. Am J Emerg Med. 2002; 20: 139–43.
- Tait IS, Ionescu MV, Cuschieri A. Do patients with acute abdominal pain wait unduly long for analgesia? J R Coll Surg Edinb. 1999; 44: 181–4.
- Thomas, SH, Shackelford, J, Borczuk, P, Godley, CD, Conn, AKT. Omission of analgesia in emergency department patients with suspected appendicitis [abstract]. Acad Emerg Med. 1997; 4: 424.
- Devellis P, Thomas SH, Wedel SK. Prehospital and emergency department analgesia for air transported patients with fractures. Prehosp Emerg Care. 1998; 2: 293–6.
- Kozlowski, MJ, Wiater, JG, Pasqual, RG, Compton, S, Swor, RA, Jackson, RE. Painful discrimination: the differential use of analgesia in isolated lower limb injuries. Am J Emerg Med. 2002; 20: 502–5.
- McEachin CC, McDermott JT, Swor R. Few emergency medical services patients with lower extremity fractures receive pre-hospital analgesia. Prehosp Emerg Care. 2002; 6: 406–10.
- Yen, K, Kim, M, Stremski, ES, Gorelick, MH. Effect of ethnicity and race in the use of pain medication in children with long bone fractures in the emergency department. Ann Emerg Med. 2003; 42: 41–7.
- Silka PA, Roth MM, Geiderman JM. Patterns of analgesic use in trauma patients in the ED. Am J Emerg Med. 2002; 20: 298–302.
- Liebeskind JC. Pain can kill. Pain. 1991; 44: 3–4.
- Lewis, KS, Whipple, JK, Michael, KA, Quebbeman, EJ. Effect of analgesic treatment on the physiological consequences of acute pain. Am J Hosp Pharm. 1994; 51: 1539–54.
- Coderre, TJ, Katz, J, Vaccarino, AL, Melzack, R. Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence. Pain. 1993; 52: 259–85.
- Jabbur SJ, Saade NE. From electrical wiring to plastic neurons: evolving approaches to the study of pain. Pain. 1999; (Suppl 6): S87–92.
- Gottschalk A, Ochroch EA. Preemptive analgesia: what do we do next? Anesthesiology. 2003; 98: 280–1.
- Zhu X, Eisenach JC. Cyclooxygenase-1 in the spinal cord is altered after peripheral nerve injury. Anesthesiology. 2003; 99: 1175–9.
- Howard RF. Current status of pain management in children. JAMA. 2003; 290: 2464–9.
- Puntillo K, Weiss SJ. Pain: its mediators and associated morbidity in critically ill cardiovascular surgical patients. Nurs Res. 1994; 43: 31–6.
- Buvanendran A, Kroin JS, Tuman KJ et al. Effects of perioperative administration of a selective cyclooxygenase 2 inhibitor on pain management and recovery of function after knee replacement: a randomized controlled trial. JAMA. 2003; 290: 2411–8.
- Kohn, MA, Hammel, JM, Bretz, SW, Stangby, A. Trauma team activation criteria as predictors of patient disposition from the emergency department. Acad Emerg Med. 2004; 11: 1–9.
- Mandelberg JH, Kuhn RE, Kohn MA. Epidemiologic analysis of an urban, public emergency department's frequent users. Acad Emerg Med. 2000; 7: 637–46.
- Fuentes EF, Kohn MA, Neighbor ML. Lack of association between patient ethnicity or race and fracture analgesia. Acad Emerg Med. 2002; 9: 910–5.
- Gilbert, EH, Lowenstein, SR, Koziol-McLain, J, Bartz, DC, Steiner, J. Chart reviews in emergency medicine research: where are the methods? Ann Emerg Med. 1996; 27: 305–8.
- Wears RL. Statistical models and Occam's razor. Acad Emerg Med. 1999; 6: 93–4.
- Silka, PA, Roth, MM, Moreno, G, Merrill, L, Geiderman, JM. Pain scores improve analgesic administration patterns for trauma patients in the emergency department. Acad Emerg Med. 2004; 11: 264–70.
-
Rupp T,
Delancy KA.
Inadequate analgesia in emergency medicine.
Ann Emerg Med.
2004; 43: 494–503.
10.1016/j.annemergmed.2003.11.019 Google Scholar
- Raftery KA, Smith-Coggins R, Chen AH. Gender-associated differences in emergency department pain management. Ann Emerg Med. 1995; 26: 414–21.
- Unruh AM. Gender variations in clinical pain experience. Pain. 1996; 65: 123–67.
- Jones JS, Johnson K, McNinch M. Age as a risk factor for inadequate emergency department analgesia. Am J Emerg Med. 1996; 14: 157–60.
- Erstad BL, Chopda S, Esser MJ. Prescribing of analgesics in trauma patients. Am J Ther. 1997; 4: 27–30.
- Puntillo KA. Dimensions of procedural pain and its analgesic management in critically ill surgical patients. Am J Crit Care. 1994; 3: 116–22.
- Puntillo KA. Pain in the critically ill Assessment and management. The Physiology of Pain and its Consequences in Critically Ill Patients., ed. Gaithers burg , MD : Aspen Publication, 1991, pp 9–27.
- Murray MJ, Plevac DJ. Analgesia in the critically ill patient. New Horiz. 1994; 2: 56–63.
-
O'Gara, PT.
The hemodynamic consequences of pain and its management.
J Intensive Care Med.
1988; 3: 3–5.
10.1177/088506668800300102 Google Scholar
- Gordon, SM, Dionne, RA, Brahim, J, Jabir, F, Dubner, R. Blockade of peripheral neuronal barrage reduces postoperative pain. Pain. 1997; 70: 209–15.
- Weisman SJ, Bernstein B, Schechter NL. Consequences of inadequate analgesia during painful procedures in children. Arch Pediatr Adolesc Med. 1998; 152: 147–9.