Erratum to “NADPH Oxidase-Induced NALP3 Inflammasome Activation Is Driven by Thioredoxin-Interacting Protein Which Contributes to Podocyte Injury in Hyperglycemia”
In Figure 6 in the paper titled “NADPH Oxidase-Induced NALP3 Inflammasome Activation Is Driven by Thioredoxin-Interacting Protein Which Contributes to Podocyte Injury in Hyperglycemia” [1], Figures 6(a) and 6(c) are completely the same pictures. This correction does not have any influence on the results and discussions of the study, which are correctly described in the text. In the published version of Gao et al., 2015, Figure 6(a) should be the representative Western blot graph of the expression of gp91phox in HG-exposed podocytes without or with TXNIP shRNA transfection. Below is the correct version of Figure 6.
Figure 6 (a)
Inhibition of TXNIP abolishes the HG-triggered upregulation of gp91phox. (a) Western blot analysis showing the expression of gp91phox in HG-exposed podocytes without or with TXNIP shRNA transfection. (b) Summarized data showing the band intensities measured from gp91phox (n = 6). (c) Western blot analysis showing the expression of TXNIP in HG-stimulated podocytes without or with gp91phox shRNA transfection. (d) Summarized data showing the band intensities measured from TXNIP (n = 6). (e) Protein expression of TXNIP in HG-stimulated podocytes without or with pretreatment of APO or DPI. (f) Summarized data showing the band intensities of TXNIP (n = 4–6). Ctrl: control; HG: high glucose; Veh: vehicle; Scram: scrambled shRNA; shTXNIP: TXNIP shRNA; shgp91: gp91phox shRNA; APO: apocynin; DPI: diphenyleneiodonium. ∗P < 0.05 compared with Ctrl; #P < 0.05 compared with HG group treated with vehicle or transfected with scramble shRNA.
Figure 6 (b)
Inhibition of TXNIP abolishes the HG-triggered upregulation of gp91phox. (a) Western blot analysis showing the expression of gp91phox in HG-exposed podocytes without or with TXNIP shRNA transfection. (b) Summarized data showing the band intensities measured from gp91phox (n = 6). (c) Western blot analysis showing the expression of TXNIP in HG-stimulated podocytes without or with gp91phox shRNA transfection. (d) Summarized data showing the band intensities measured from TXNIP (n = 6). (e) Protein expression of TXNIP in HG-stimulated podocytes without or with pretreatment of APO or DPI. (f) Summarized data showing the band intensities of TXNIP (n = 4–6). Ctrl: control; HG: high glucose; Veh: vehicle; Scram: scrambled shRNA; shTXNIP: TXNIP shRNA; shgp91: gp91phox shRNA; APO: apocynin; DPI: diphenyleneiodonium. ∗P < 0.05 compared with Ctrl; #P < 0.05 compared with HG group treated with vehicle or transfected with scramble shRNA.
Figure 6 (c)
Inhibition of TXNIP abolishes the HG-triggered upregulation of gp91phox. (a) Western blot analysis showing the expression of gp91phox in HG-exposed podocytes without or with TXNIP shRNA transfection. (b) Summarized data showing the band intensities measured from gp91phox (n = 6). (c) Western blot analysis showing the expression of TXNIP in HG-stimulated podocytes without or with gp91phox shRNA transfection. (d) Summarized data showing the band intensities measured from TXNIP (n = 6). (e) Protein expression of TXNIP in HG-stimulated podocytes without or with pretreatment of APO or DPI. (f) Summarized data showing the band intensities of TXNIP (n = 4–6). Ctrl: control; HG: high glucose; Veh: vehicle; Scram: scrambled shRNA; shTXNIP: TXNIP shRNA; shgp91: gp91phox shRNA; APO: apocynin; DPI: diphenyleneiodonium. ∗P < 0.05 compared with Ctrl; #P < 0.05 compared with HG group treated with vehicle or transfected with scramble shRNA.
Figure 6 (d)
Inhibition of TXNIP abolishes the HG-triggered upregulation of gp91phox. (a) Western blot analysis showing the expression of gp91phox in HG-exposed podocytes without or with TXNIP shRNA transfection. (b) Summarized data showing the band intensities measured from gp91phox (n = 6). (c) Western blot analysis showing the expression of TXNIP in HG-stimulated podocytes without or with gp91phox shRNA transfection. (d) Summarized data showing the band intensities measured from TXNIP (n = 6). (e) Protein expression of TXNIP in HG-stimulated podocytes without or with pretreatment of APO or DPI. (f) Summarized data showing the band intensities of TXNIP (n = 4–6). Ctrl: control; HG: high glucose; Veh: vehicle; Scram: scrambled shRNA; shTXNIP: TXNIP shRNA; shgp91: gp91phox shRNA; APO: apocynin; DPI: diphenyleneiodonium. ∗P < 0.05 compared with Ctrl; #P < 0.05 compared with HG group treated with vehicle or transfected with scramble shRNA.
Figure 6 (e)
Inhibition of TXNIP abolishes the HG-triggered upregulation of gp91phox. (a) Western blot analysis showing the expression of gp91phox in HG-exposed podocytes without or with TXNIP shRNA transfection. (b) Summarized data showing the band intensities measured from gp91phox (n = 6). (c) Western blot analysis showing the expression of TXNIP in HG-stimulated podocytes without or with gp91phox shRNA transfection. (d) Summarized data showing the band intensities measured from TXNIP (n = 6). (e) Protein expression of TXNIP in HG-stimulated podocytes without or with pretreatment of APO or DPI. (f) Summarized data showing the band intensities of TXNIP (n = 4–6). Ctrl: control; HG: high glucose; Veh: vehicle; Scram: scrambled shRNA; shTXNIP: TXNIP shRNA; shgp91: gp91phox shRNA; APO: apocynin; DPI: diphenyleneiodonium. ∗P < 0.05 compared with Ctrl; #P < 0.05 compared with HG group treated with vehicle or transfected with scramble shRNA.
Figure 6 (f)
Inhibition of TXNIP abolishes the HG-triggered upregulation of gp91phox. (a) Western blot analysis showing the expression of gp91phox in HG-exposed podocytes without or with TXNIP shRNA transfection. (b) Summarized data showing the band intensities measured from gp91phox (n = 6). (c) Western blot analysis showing the expression of TXNIP in HG-stimulated podocytes without or with gp91phox shRNA transfection. (d) Summarized data showing the band intensities measured from TXNIP (n = 6). (e) Protein expression of TXNIP in HG-stimulated podocytes without or with pretreatment of APO or DPI. (f) Summarized data showing the band intensities of TXNIP (n = 4–6). Ctrl: control; HG: high glucose; Veh: vehicle; Scram: scrambled shRNA; shTXNIP: TXNIP shRNA; shgp91: gp91phox shRNA; APO: apocynin; DPI: diphenyleneiodonium. ∗P < 0.05 compared with Ctrl; #P < 0.05 compared with HG group treated with vehicle or transfected with scramble shRNA.
