Penile transplantation: an emerging option for genitourinary reconstruction
Sami H. Tuffaha
Department of Plastic and Reconstructive Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorDamon S. Cooney
Department of Plastic and Reconstructive Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorNikolai A. Sopko
Department of Urology, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorTrinity J. Bivalacqua
Department of Urology, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorDenver M. Lough
Department of Plastic and Reconstructive Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorCarisa M. Cooney
Department of Plastic and Reconstructive Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorGerald Brandacher
Department of Plastic and Reconstructive Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorWei-Ping Andrew Lee
Department of Plastic and Reconstructive Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorArthur L. Burnett II
Department of Urology, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorCorresponding Author
Richard J. Redett
Department of Plastic and Reconstructive Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Correspondence
Richard J. Redett MD, Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, 801 N. Caroline Street, 8th floor Baltimore, MD 21287, USA.
Tel.: 410-955-9475;
fax: 410-955-7060;
e-mail: [email protected]
Search for more papers by this authorSami H. Tuffaha
Department of Plastic and Reconstructive Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorDamon S. Cooney
Department of Plastic and Reconstructive Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorNikolai A. Sopko
Department of Urology, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorTrinity J. Bivalacqua
Department of Urology, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorDenver M. Lough
Department of Plastic and Reconstructive Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorCarisa M. Cooney
Department of Plastic and Reconstructive Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorGerald Brandacher
Department of Plastic and Reconstructive Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorWei-Ping Andrew Lee
Department of Plastic and Reconstructive Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorArthur L. Burnett II
Department of Urology, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Search for more papers by this authorCorresponding Author
Richard J. Redett
Department of Plastic and Reconstructive Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Correspondence
Richard J. Redett MD, Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, 801 N. Caroline Street, 8th floor Baltimore, MD 21287, USA.
Tel.: 410-955-9475;
fax: 410-955-7060;
e-mail: [email protected]
Search for more papers by this authorSummary
Penile transplantation is an emerging option for patients with severe genital defects not amenable to traditional reconstructive options. In this article, we discuss the burgeoning problem of severe male genitourinary trauma in the military, the limitations of traditional reconstructive options in addressing these problems, and the potential for penile transplantation to provide improved outcomes. We also review the preclinical research and limited worldwide experience with penile transplantation to date, including lessons learned, and discuss the many important technical, logistical, and ethical considerations pertaining to penile transplantation that must be addressed to maximize the likelihood of successful implementation.
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