Disseminated toxoplasmosis associated with hemophagocytic syndrome after kidney transplantation: A case report and review
Juliette Gay
Parasitology and mycology laboratory, Bichat-Claude Bernard Hospital, APHP, Paris, France
Faculty of Pharmacy, Paris Descartes University, Sorbonne Paris Cité, Paris, France
Search for more papers by this authorNicolas Gendron
Faculty of Pharmacy, Paris Descartes University, Sorbonne Paris Cité, Paris, France
Hematology laboratory, Bichat-Claude Bernard Hospital, APHP, Paris, France
INSERM, UMR 1148, Paris, France
Search for more papers by this authorCharles Verney
Nephrology department, Bichat-Claude Bernard Hospital, APHP, Paris, France
Search for more papers by this authorValentin Joste
Parasitology and mycology laboratory, Bichat-Claude Bernard Hospital, APHP, Paris, France
Faculty of Pharmacy, Paris Descartes University, Sorbonne Paris Cité, Paris, France
Institute for Research and Development (IRD), MERIT UMR 216, Paris Descartes University, Paris, France
Search for more papers by this authorMarie-Laure Dardé
INSERM, UMR-S 1094 Tropical Neuroepidemiology, Limoges, France
Parasitology laboratory, University Hospital Center of Limoges, Limoges, France
Search for more papers by this authorCharlotte Loheac
Nephrology department, Bichat-Claude Bernard Hospital, APHP, Paris, France
Search for more papers by this authorFrançois Vrtovsnik
Nephrology department, Bichat-Claude Bernard Hospital, APHP, Paris, France
Faculty of Medicine, Paris Diderot University, Sorbonne Paris Cité, Paris, France
Search for more papers by this authorCorresponding Author
Nicolas Argy
Parasitology and mycology laboratory, Bichat-Claude Bernard Hospital, APHP, Paris, France
Faculty of Pharmacy, Paris Descartes University, Sorbonne Paris Cité, Paris, France
Institute for Research and Development (IRD), MERIT UMR 216, Paris Descartes University, Paris, France
Correspondence
Nicolas Argy, Parasitology and mycology laboratory, Bichat-Claude Bernard Hospital, APHP, Paris, France.
Email: [email protected]
Search for more papers by this authorSandrine Houze
Parasitology and mycology laboratory, Bichat-Claude Bernard Hospital, APHP, Paris, France
Faculty of Pharmacy, Paris Descartes University, Sorbonne Paris Cité, Paris, France
Institute for Research and Development (IRD), MERIT UMR 216, Paris Descartes University, Paris, France
Search for more papers by this authorJuliette Gay
Parasitology and mycology laboratory, Bichat-Claude Bernard Hospital, APHP, Paris, France
Faculty of Pharmacy, Paris Descartes University, Sorbonne Paris Cité, Paris, France
Search for more papers by this authorNicolas Gendron
Faculty of Pharmacy, Paris Descartes University, Sorbonne Paris Cité, Paris, France
Hematology laboratory, Bichat-Claude Bernard Hospital, APHP, Paris, France
INSERM, UMR 1148, Paris, France
Search for more papers by this authorCharles Verney
Nephrology department, Bichat-Claude Bernard Hospital, APHP, Paris, France
Search for more papers by this authorValentin Joste
Parasitology and mycology laboratory, Bichat-Claude Bernard Hospital, APHP, Paris, France
Faculty of Pharmacy, Paris Descartes University, Sorbonne Paris Cité, Paris, France
Institute for Research and Development (IRD), MERIT UMR 216, Paris Descartes University, Paris, France
Search for more papers by this authorMarie-Laure Dardé
INSERM, UMR-S 1094 Tropical Neuroepidemiology, Limoges, France
Parasitology laboratory, University Hospital Center of Limoges, Limoges, France
Search for more papers by this authorCharlotte Loheac
Nephrology department, Bichat-Claude Bernard Hospital, APHP, Paris, France
Search for more papers by this authorFrançois Vrtovsnik
Nephrology department, Bichat-Claude Bernard Hospital, APHP, Paris, France
Faculty of Medicine, Paris Diderot University, Sorbonne Paris Cité, Paris, France
Search for more papers by this authorCorresponding Author
Nicolas Argy
Parasitology and mycology laboratory, Bichat-Claude Bernard Hospital, APHP, Paris, France
Faculty of Pharmacy, Paris Descartes University, Sorbonne Paris Cité, Paris, France
Institute for Research and Development (IRD), MERIT UMR 216, Paris Descartes University, Paris, France
Correspondence
Nicolas Argy, Parasitology and mycology laboratory, Bichat-Claude Bernard Hospital, APHP, Paris, France.
Email: [email protected]
Search for more papers by this authorSandrine Houze
Parasitology and mycology laboratory, Bichat-Claude Bernard Hospital, APHP, Paris, France
Faculty of Pharmacy, Paris Descartes University, Sorbonne Paris Cité, Paris, France
Institute for Research and Development (IRD), MERIT UMR 216, Paris Descartes University, Paris, France
Search for more papers by this authorAbstract
Disseminated toxoplasmosis is infrequent after kidney transplant transmission but life-threatening because of a lack of diagnostic suspicion as well as specific chemoprophylaxis recommendations. Solid organ transplantation has resulted in few cases of disseminated toxoplasmosis presenting with associated hemophagocytic syndrome. Herein, we report, within the context of a donor/receiver mismatch, a case of a toxoplasmosis associated with hemophagocytic syndrome in a kidney transplant recipient. Molecular and serological investigations confirmed Toxoplasma gondii transmission through the kidney graft.
CONFLICTS OF INTEREST
The authors of this manuscript have no conflicts of interest.
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