Small effort, high impact: Focus on physical activity improves oxygen uptake (VO2peak), quality of life, and mental health after pediatric renal transplantation
Corresponding Author
Hjørdis Thorsteinsdottir
Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Pediatric Research Institute, Oslo University Hospital, Oslo, Norway
Correspondence
Hjordis Thorsteinsdottir, Division of Paediatric and Adolescent Medicine, Oslo University Hospital HF, Rikshospitalet, Oslo, Norway.
Email: [email protected]
Search for more papers by this authorTrond H. Diseth
Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Search for more papers by this authorAnine Lie
Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Search for more papers by this authorTrine Tangeraas
Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway
Search for more papers by this authorIren Matthews
Department of Paediatric Allergy and Pulmonology, Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway
Search for more papers by this authorAnders Åsberg
Department of Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway
Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo, Norway
Search for more papers by this authorAnna Bjerre
Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway
Search for more papers by this authorCorresponding Author
Hjørdis Thorsteinsdottir
Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Pediatric Research Institute, Oslo University Hospital, Oslo, Norway
Correspondence
Hjordis Thorsteinsdottir, Division of Paediatric and Adolescent Medicine, Oslo University Hospital HF, Rikshospitalet, Oslo, Norway.
Email: [email protected]
Search for more papers by this authorTrond H. Diseth
Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Search for more papers by this authorAnine Lie
Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Search for more papers by this authorTrine Tangeraas
Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway
Search for more papers by this authorIren Matthews
Department of Paediatric Allergy and Pulmonology, Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway
Search for more papers by this authorAnders Åsberg
Department of Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway
Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo, Norway
Search for more papers by this authorAnna Bjerre
Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway
Search for more papers by this authorAbstract
This study estimates the effects on peak oxygen uptake (VO2 peak), QoL, and mental health after the introduction of an adjusted post-transplant follow-up program, that is, early physiotherapy and focus on the importance of physical activity. VO2 peak was measured by a treadmill exercise test in 20 renal-transplanted children on the adjusted post-transplant follow-up and compared with a group of 22 patients investigated in a previously, before the implementation of our new follow-up routines. PedsQL and The Strengths and Difficulties Questionnaire (SDQ) were used to assess QoL and mental health in 45 patients on the new as compared to 32 patients on the previous follow-up strategy. The patients exposed to early physiotherapy and a higher focus on physical activity had significantly higher VO2 peak (44.3 vs 33.5 mL kg−1 min−1, P = .031) in addition to improved QoL (P = .003) and mental health scores (P = .012). The cardiovascular risk profile was similar in both groups aside from significantly higher triglycerides in the present cohort. Small efforts as early physiotherapy and increased focus on physical activity after pediatric renal transplantation have significant impact on cardiorespiratory fitness, QoL, and mental health. The importance of physical activity should therefore be emphasized in follow-up programs.
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