Vitamin D status in children with attention-deficit–hyperactivity disorder
Corresponding Author
Sevil Bilir Goksugur
Department of Pediatrics, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey
Correspondence: Sevil Bilir Goksugur, MD, Department of Pediatrics, Medical Faculty, Abant Izzet Baysal University, 14280 Golkoy – Bolu, Turkey. Email: [email protected]Search for more papers by this authorAli Evren Tufan
Department of Child and Adolescent Psychiatry, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey
Search for more papers by this authorMurat Semiz
Department of Psychiatry, Sivas State Hospital, Sivas, Turkey
Search for more papers by this authorCemalettin Gunes
Department of Pediatrics, Medical Faculty, Duzce University, Duzce, Turkey
Search for more papers by this authorMervan Bekdas
Department of Pediatrics, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey
Search for more papers by this authorMehmet Tosun
Department of Biochemistry, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey
Search for more papers by this authorFatih Demircioglu
Department of Pediatrics, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey
Search for more papers by this authorCorresponding Author
Sevil Bilir Goksugur
Department of Pediatrics, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey
Correspondence: Sevil Bilir Goksugur, MD, Department of Pediatrics, Medical Faculty, Abant Izzet Baysal University, 14280 Golkoy – Bolu, Turkey. Email: [email protected]Search for more papers by this authorAli Evren Tufan
Department of Child and Adolescent Psychiatry, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey
Search for more papers by this authorMurat Semiz
Department of Psychiatry, Sivas State Hospital, Sivas, Turkey
Search for more papers by this authorCemalettin Gunes
Department of Pediatrics, Medical Faculty, Duzce University, Duzce, Turkey
Search for more papers by this authorMervan Bekdas
Department of Pediatrics, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey
Search for more papers by this authorMehmet Tosun
Department of Biochemistry, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey
Search for more papers by this authorFatih Demircioglu
Department of Pediatrics, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey
Search for more papers by this authorAbstract
Background
Attention-deficit–hyperactivity disorder (ADHD), one of the most common psychiatric disorders of childhood, has an early onset, affecting 2–18% of children worldwide. The etiopathogenesis of ADHD is obscure. In recent studies, a low level of vitamin D has been found in association with many disorders as well as in neuropsychiatric diseases. The aim of this study was therefore to investigate serum vitamin D level in pediatric ADHD patients.
Methods
A total of 60 ADHD patients and 30 healthy controls were included in the study. The age of both groups was in the 7–18-year-old range. Serum 25-OH-vitamin D, calcium, phosphorus and alkaline phosphatase were investigated.
Results
Serum 25-OH-vitamin D was found to be significantly lower in children and adolescents with ADHD compared to healthy controls, and no significant differences were found between the groups in terms of other variables. 25-OH-vitamin D level in the ADHD group and control group was, respectively, 20.9 ± 19.4 ng/mL and 34.9 ± 15.4 ng/mL (P = 0.001).
Conclusion
There is an association between lower 25-OH-vitamin D concentration and ADHD in childhood and adolescence. To the authors' knowledge this is the first study to investigate the relationship between vitamin D and ADHD in children.
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