Volume 33, Issue 2 pp. e95-e98
Case Report

Radiologic Improvement After Early Medical Intervention in Localised Facial Morphea

Muhammad Amjad Khan M.Sc., F.R.C.P.C.H. (UK)

Corresponding Author

Muhammad Amjad Khan M.Sc., F.R.C.P.C.H. (UK)

Paediatric Dermatology, Great Ormond Street Hospital, London, UK

Address correspondence to M. Amjad Khan, M.Sc., Registrar, Paediatric Dermatology, Great Ormond Street Hospital, Level 6, Southwood Building Great Ormond Street, London WC1N 3JH, UK, or e-mail: [email protected].Search for more papers by this author
Lindsay Shaw F.R.C.P. (UK), F.R.C.P.C.H. (UK)

Lindsay Shaw F.R.C.P. (UK), F.R.C.P.C.H. (UK)

Paediatric Dermatology, Great Ormond Street Hospital, London, UK

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Despina Eleftheriou Ph.D., M.R.C.P.C.H. (UK)

Despina Eleftheriou Ph.D., M.R.C.P.C.H. (UK)

Paediatric Rheumatology, Great Ormond Street Hospital, London, UK

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Prab Prabhakar F.R.C.P.C.H. (UK)

Prab Prabhakar F.R.C.P.C.H. (UK)

Paediatric Neurology, Great Ormond Street Hospital, London, UK

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Wui K. Chong M.D., F.R.C.R. (UK)

Wui K. Chong M.D., F.R.C.R. (UK)

Paediatric Neuro-Radiology, Great Ormond Street Hospital, London, UK

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Mary Glover M.A., F.R.C.P. (UK), F.R.C.P.C.H. (UK)

Mary Glover M.A., F.R.C.P. (UK), F.R.C.P.C.H. (UK)

Paediatric Dermatology, Great Ormond Street Hospital, London, UK

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First published: 10 February 2016
Citations: 7

Abstract

We report the case of a young girl who presented with hemiparesis, seizures, and subtle features consistent with a linear form of facial morphea (en coup de sabre). She was treated with pulsed parenteral steroids and oral steroids and started on methotrexate. Magnetic resonance imaging results and neurologic problems improved after 6 months. Switching off inflammation early in the course of disease seemed to reverse some of the central nervous system changes. Assessment of children with unexplained hemiparesis and seizures should include careful examination of the face and scalp, looking for subtle signs of skin change and asymmetry. This is one of the few reported cases of neuroradiologic improvement after immunosuppressive treatment in a child with en coup de sabre.

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