Clinical Outcomes and Complications of Carotid Artery Stenting With or Without Pre-Stent and Post-Stent Balloon Angioplasty
Maria Martucci
Cleveland Clinic, Cleveland, Ohio, USA
Maria Martucci and Mohamad Ezzeldin are Co-First Author
Search for more papers by this authorCorresponding Author
Mohamad Ezzeldin
HCA Houston Healthcare Kingwood, Kingwood, Texas, USA
Maria Martucci and Mohamad Ezzeldin are Co-First Author
Search for more papers by this authorKaho Adachi
University of Illinois College of Medicine at Chicago, Chicago, Illinois, USA
Search for more papers by this authorAdam Delora
HCA Houston Healthcare Kingwood, Kingwood, Texas, USA
Search for more papers by this authorRime Ezzeldin
Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan
Search for more papers by this authorAmeer E. Hassan
Valley Baptist Medical Center, Harlingen, Texas, USA
Search for more papers by this authorFaheem G. Sheriff
Texas Tech University Health Sciences Center, El Paso, Texas, USA
Search for more papers by this authorPeter Kan
University of Texas Medical Branch (UTMB), Galveston, Texas, USA
Search for more papers by this authorNazli Janjua
Pomona Valley Hospital Medical Center, Pomona, California, USA
Search for more papers by this authorAli Alaraj
University of Illinois Chicago (UIC), Chicago, Illinois, USA
Search for more papers by this authorOmar Tanweer
Baylor St. Lukes Medical Center, Houston, Texas, USA
Search for more papers by this authorSamantha Miller
Valley Baptist Medical Center, Harlingen, Texas, USA
Search for more papers by this authorNavpreet K. Bains
University of Missouri, Columbia, Missouri, USA
Search for more papers by this authorGabriela Colina
Texas Tech University Health Sciences Center, El Paso, Texas, USA
Search for more papers by this authorMohammad AlMajali
St. Vincent Medical Center, Toledo, Ohio, USA
Search for more papers by this authorGautam Edhayan
University of Texas Medical Branch (UTMB), Galveston, Texas, USA
Search for more papers by this authorElsa Nico
University of Illinois Chicago (UIC), Chicago, Illinois, USA
Search for more papers by this authorYazan Radaideh
Rush University Medical Center, Chicago, Illinois, USA
Search for more papers by this authorMaria Martucci
Cleveland Clinic, Cleveland, Ohio, USA
Maria Martucci and Mohamad Ezzeldin are Co-First Author
Search for more papers by this authorCorresponding Author
Mohamad Ezzeldin
HCA Houston Healthcare Kingwood, Kingwood, Texas, USA
Maria Martucci and Mohamad Ezzeldin are Co-First Author
Search for more papers by this authorKaho Adachi
University of Illinois College of Medicine at Chicago, Chicago, Illinois, USA
Search for more papers by this authorAdam Delora
HCA Houston Healthcare Kingwood, Kingwood, Texas, USA
Search for more papers by this authorRime Ezzeldin
Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan
Search for more papers by this authorAmeer E. Hassan
Valley Baptist Medical Center, Harlingen, Texas, USA
Search for more papers by this authorFaheem G. Sheriff
Texas Tech University Health Sciences Center, El Paso, Texas, USA
Search for more papers by this authorPeter Kan
University of Texas Medical Branch (UTMB), Galveston, Texas, USA
Search for more papers by this authorNazli Janjua
Pomona Valley Hospital Medical Center, Pomona, California, USA
Search for more papers by this authorAli Alaraj
University of Illinois Chicago (UIC), Chicago, Illinois, USA
Search for more papers by this authorOmar Tanweer
Baylor St. Lukes Medical Center, Houston, Texas, USA
Search for more papers by this authorSamantha Miller
Valley Baptist Medical Center, Harlingen, Texas, USA
Search for more papers by this authorNavpreet K. Bains
University of Missouri, Columbia, Missouri, USA
Search for more papers by this authorGabriela Colina
Texas Tech University Health Sciences Center, El Paso, Texas, USA
Search for more papers by this authorMohammad AlMajali
St. Vincent Medical Center, Toledo, Ohio, USA
Search for more papers by this authorGautam Edhayan
University of Texas Medical Branch (UTMB), Galveston, Texas, USA
Search for more papers by this authorElsa Nico
University of Illinois Chicago (UIC), Chicago, Illinois, USA
Search for more papers by this authorYazan Radaideh
Rush University Medical Center, Chicago, Illinois, USA
Search for more papers by this authorFunding: The authors received no specific funding for this work.
ABSTRACT
Background and Purpose
Carotid artery stenting is a well-established method for treating carotid artery stenosis; however, there are conflicting data on prestenting versus post-stenting balloon angioplasty. Our study aims to understand the risk and safety of pre-stent balloon angioplasty (Pre-SB) and post-stent balloon angioplasty (Post-SB), or both techniques.
Methods
Multicenter retrospective data on angioplasty balloons, stents, complications, and modified Rankin score (mRS) before and after the procedure were collected. Statistical analysis was performed to correlate with complication risks and clinical outcomes.
Results
1,355 patients were enrolled. Post-SB predicted fewer complications (p = 0.035) than Pre-SB or combined Pre-SB and Post-SB. Female sex was a predictor of complications (p = 0.041), while utilization of an embolic protection device predicted fewer complications (p < 0.001). Increasing age (p < 0.001) and smoking (p = 0.027) predicted increased length of stay. Using open-cell stents versus closed-cell stents did not predict follow-up modified rankin score (mRS) or complications, but using open-cell stents did predict a shorter length of stay. Conversely, open-cell stents were more likely to undergo Post-SB (p < 0.001), while closed-cell stents were more likely to undergo Pre-SB (p = 0.002).
Conclusions
Unlike previous literature, our results showed that Post-SB alone was associated with fewer complications compared to either Pre-SB alone or the combination of Pre-SB and Post-SB. Open-cell stents required a higher rate of Post-SB.
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