Volume 21, Issue 8 pp. 3256-3264
REVIEW ARTICLE

Studies on stratum corneum metabolism: function, molecular mechanism and influencing factors

Qian Jiao BS

Qian Jiao BS

Key Laboratory of Cosmetic of China National Light Industry, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, China

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Lizhi Yue MS

Lizhi Yue MS

School of Chemistry and Chemical Engineering, Qilu Normal University, Shandong, China

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Leilei Zhi MS

Leilei Zhi MS

Shandong Huawutang Biological Technology Co., Ltd, Shandong, China

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Yufeng Qi MS

Yufeng Qi MS

Shandong Huawutang Biological Technology Co., Ltd, Shandong, China

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Jie Yang MS

Jie Yang MS

Shandong Huawutang Biological Technology Co., Ltd, Shandong, China

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Cheng Zhou MD

Cheng Zhou MD

Department of Dermatology, Peking University People’s Hospital, Beijing, China

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Yan Jia PhD

Corresponding Author

Yan Jia PhD

Key Laboratory of Cosmetic of China National Light Industry, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, China

Correspondence

Yan Jia, Key Laboratory of Cosmetic of China National Light Industry, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, China.

Email: [email protected]

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First published: 18 April 2022
Citations: 6

Funding information

None.

Qian Jiao and Lizhi Yue contributed equally to this work.

Abstract

Background

Stratum corneum is located in the outermost layer of the skin and is the most important part of the skin barrier. Stratum corneum mainly contains keratinocytes, lipids, and desmosomes. Their normal metabolic process is closely related to the function of skin barrier.

Aims

This paper reviews the structure and function of stratum corneum, influencing factors, skin diseases, and common solutions.

Methods

An extensive literature search was conducted on the structure and function of stratum corneum, influencing factors, skin diseases, and common solutions.

Results

This paper reviews the structure and function of stratum corneum and the influence of various factors on stratum corneum metabolism. At the same time, the existing skin problems, skin diseases, and common solutions are summarized.

Conclusions

This information will help to understand the function, molecular mechanism, and influencing factors of stratum corneum metabolism, and provide new ideas for stratum corneum health management and cosmetic research and development.

CONFLICT OF INTEREST

The authors declare that they have no conflict of interest.

DATA AVAILABILITY STATEMENT

Data sharing not applicable to this article as no datasets were generated or analysed during the current study.

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