Extracorporeal shock wave lithotripsy is safe and effective for geriatric patients with chronic pancreatitis
Correction(s) for this article
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Corrigendum
- Volume 35Issue 5Journal of Gastroenterology and Hepatology
- pages: 905-905
- First Published online: May 4, 2020
Lu Hao
Department of Gastroenterology, Hainan Branch of Chinese PLA General Hospital, Sanya, China
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Drs Hao, Liu, and Wang contributed equally to this study.Search for more papers by this authorYu Liu
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Drs Hao, Liu, and Wang contributed equally to this study.Search for more papers by this authorTeng Wang
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, Shanghai, China
Drs Hao, Liu, and Wang contributed equally to this study.Search for more papers by this authorHong-Lei Guo
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorDan Wang
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorYa-Wei Bi
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorLei Xin
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorLin He
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorJin-Huan Lin
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorDi Zhang
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorXiang-Peng Zeng
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorWen-Bin Zou
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorHui Chen
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorTing Xie
Department of Gastroenterology, Zhongda Hospital, Southeast University, Nanjing, China
Search for more papers by this authorBai-Rong Li
Department of Gastroenterology, Air Force General Hospital, Beijing, China
Search for more papers by this authorZhi-Jie Cong
Department of General Surgery, Renji Hospital, Shanghai Jiaotong University, Shanghai, China
Search for more papers by this authorLi-Sheng Wang
Department of Gastroenterology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenzhen, China
Search for more papers by this authorZhuan Liao
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorCorresponding Author
Zheng-Lei Xu
Department of Gastroenterology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenzhen, China
Correspondence
Dr Liang-Hao Hu and Dr Zhao-Shen Li, Department of Gastroenterology, Gongli Hospital, Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, 800 Xiangyin Road, Shanghai 200433, China.
Email: [email protected]; [email protected]
Dr Zheng-Lei Xu, Department of Gastroenterology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, 1017 North Dongmen Road, Guangdong, China.
Email: [email protected]
Search for more papers by this authorCorresponding Author
Zhao-Shen Li
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, Shanghai, China
Correspondence
Dr Liang-Hao Hu and Dr Zhao-Shen Li, Department of Gastroenterology, Gongli Hospital, Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, 800 Xiangyin Road, Shanghai 200433, China.
Email: [email protected]; [email protected]
Dr Zheng-Lei Xu, Department of Gastroenterology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, 1017 North Dongmen Road, Guangdong, China.
Email: [email protected]
Search for more papers by this authorCorresponding Author
Liang-Hao Hu
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, Shanghai, China
Correspondence
Dr Liang-Hao Hu and Dr Zhao-Shen Li, Department of Gastroenterology, Gongli Hospital, Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, 800 Xiangyin Road, Shanghai 200433, China.
Email: [email protected]; [email protected]
Dr Zheng-Lei Xu, Department of Gastroenterology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, 1017 North Dongmen Road, Guangdong, China.
Email: [email protected]
Search for more papers by this authorLu Hao
Department of Gastroenterology, Hainan Branch of Chinese PLA General Hospital, Sanya, China
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Drs Hao, Liu, and Wang contributed equally to this study.Search for more papers by this authorYu Liu
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Drs Hao, Liu, and Wang contributed equally to this study.Search for more papers by this authorTeng Wang
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, Shanghai, China
Drs Hao, Liu, and Wang contributed equally to this study.Search for more papers by this authorHong-Lei Guo
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorDan Wang
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorYa-Wei Bi
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorLei Xin
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorLin He
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorJin-Huan Lin
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorDi Zhang
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorXiang-Peng Zeng
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorWen-Bin Zou
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorHui Chen
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorTing Xie
Department of Gastroenterology, Zhongda Hospital, Southeast University, Nanjing, China
Search for more papers by this authorBai-Rong Li
Department of Gastroenterology, Air Force General Hospital, Beijing, China
Search for more papers by this authorZhi-Jie Cong
Department of General Surgery, Renji Hospital, Shanghai Jiaotong University, Shanghai, China
Search for more papers by this authorLi-Sheng Wang
Department of Gastroenterology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenzhen, China
Search for more papers by this authorZhuan Liao
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, Shanghai, China
Search for more papers by this authorCorresponding Author
Zheng-Lei Xu
Department of Gastroenterology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenzhen, China
Correspondence
Dr Liang-Hao Hu and Dr Zhao-Shen Li, Department of Gastroenterology, Gongli Hospital, Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, 800 Xiangyin Road, Shanghai 200433, China.
Email: [email protected]; [email protected]
Dr Zheng-Lei Xu, Department of Gastroenterology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, 1017 North Dongmen Road, Guangdong, China.
Email: [email protected]
Search for more papers by this authorCorresponding Author
Zhao-Shen Li
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, Shanghai, China
Correspondence
Dr Liang-Hao Hu and Dr Zhao-Shen Li, Department of Gastroenterology, Gongli Hospital, Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, 800 Xiangyin Road, Shanghai 200433, China.
Email: [email protected]; [email protected]
Dr Zheng-Lei Xu, Department of Gastroenterology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, 1017 North Dongmen Road, Guangdong, China.
Email: [email protected]
Search for more papers by this authorCorresponding Author
Liang-Hao Hu
Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China
Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, Shanghai, China
Correspondence
Dr Liang-Hao Hu and Dr Zhao-Shen Li, Department of Gastroenterology, Gongli Hospital, Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, 800 Xiangyin Road, Shanghai 200433, China.
Email: [email protected]; [email protected]
Dr Zheng-Lei Xu, Department of Gastroenterology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, 1017 North Dongmen Road, Guangdong, China.
Email: [email protected]
Search for more papers by this authorAbstract
Background and Aim
Pancreatic extracorporeal shock wave lithotripsy (P-ESWL) is a first-line treatment for chronic pancreatitis (CP) patients with pancreatic stones. However, the performance of P-EWSL in geriatric patients remains unclear. We aimed to evaluate the safety and efficacy of P-ESWL for them.
Methods
This prospective study was conducted in painful CP patients who underwent P-ESWL. Patients aged over 65 years were included in geriatric group; patients aged under 65 years were assigned to control group. For the long-term follow-up investigation, geriatric patients were matched with patients from the control group in a 1:1 ratio. Primary outcomes were complications of P-ESWL and pain relief. Secondary outcomes included stone clearance, physical and mental health, quality of life score, changes in exocrine and endocrine pancreatic function, and survival.
Results
From March 2011 to March 2016, P-ESWL was performed in 1404 patients (72 in the geriatric group and 1332 in the control group). No significant differences were observed in complications of P-ESWL between the two groups (P = 0.364). Among the 67 (67/72, 93.1%) geriatric patients who underwent follow up for 4.02 years, complete pain relief was achieved in 53 patients, which was not significantly different from that of matched controls (54/70; P = 0.920). The death in the geriatrics was significantly higher (P = 0.007), but none of them were correlated with P-ESWL.
Conclusions
P-ESWL is safe and effective for geriatric CP patients with pancreatic stones. It can promote significant pain relief and stone clearance and improve quality of life and mental and physical health.
Supporting Information
| Filename | Description |
|---|---|
| jgh14569-sup-0001-SI.tifTIFF image, 2.9 MB |
Figure S1. Mean ages of CP patients in different countries. This scatter plot was based on the ages and times reported by each study of CP (References see Supplementary material 1). Unit root test was adopted to test the stationarity of these series, with P < 0.05 indicating stationary. They were analyzed by using the tseries package of R, version 3.2.4 (http://www.rproject.org/; America: P = 0.457; Europe: P = 0.544; China: P = 0.033; India: P = 0.809). CP = chronic pancreatitis. |
| jgh14569-sup-0002-SI.docxWord 2007 document , 14.4 KB |
Table S1. Definitions of major adverse events of pancreatic extracorporeal shock wave lithotripsy. |
| jgh14569-sup-0003-SI.docxWord 2007 document , 19.2 KB |
Table S2. Coexisted diseases at pancreatic extracorporeal shock wave lithotripsy (P-ESWL). |
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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