Volume 35, Issue 6 pp. 821-833
CLINICAL ARTICLE

Whitening efficacy and tooth sensitivity in a combined in-office and at-home whitening protocol: A randomized controlled clinical trial

Toshiki Takamizawa DDS, PhD

Corresponding Author

Toshiki Takamizawa DDS, PhD

Department of Operative Dentistry, Nihon University School of Dentistry, Tokyo, Japan

Correspondence

Toshiki Takamizawa, Department of Operative Dentistry, Nihon University School of Dentistry, 1-8-13, Kanda-Surugadai, Chiyoda-ku, Tokyo 101-8310, Japan.

Email: [email protected]

Search for more papers by this author
Ryota Aoki DDS

Ryota Aoki DDS

Department of Operative Dentistry, Nihon University School of Dentistry, Tokyo, Japan

Search for more papers by this author
Makoto Saegusa DDS

Makoto Saegusa DDS

Department of Operative Dentistry, Nihon University School of Dentistry, Tokyo, Japan

Search for more papers by this author
Eizo Hirokane DDS

Eizo Hirokane DDS

Department of Operative Dentistry, Nihon University School of Dentistry, Tokyo, Japan

Search for more papers by this author
Mone Shoji DDS

Mone Shoji DDS

Department of Operative Dentistry, Nihon University School of Dentistry, Tokyo, Japan

Search for more papers by this author
Munenori Yokoyama DDS

Munenori Yokoyama DDS

Department of Operative Dentistry, Nihon University School of Dentistry, Tokyo, Japan

Search for more papers by this author
Atsushi Kamimoto DDS, PhD

Atsushi Kamimoto DDS, PhD

Department of Comprehensive Dentistry and Clinical Education, Nihon University School of Dentistry, Tokyo, Japan

Search for more papers by this author
Masashi Miyazaki DDS, PhD

Masashi Miyazaki DDS, PhD

Department of Operative Dentistry, Nihon University School of Dentistry, Tokyo, Japan

Search for more papers by this author
First published: 08 March 2023
Citations: 2

Abstract

Objective

This controlled randomized clinical trial determined the whitening efficacy and the intensity and absolute risk of tooth sensitivity in dual whitening when prefilled at-home whitening trays were used between in-office whitening intervals.

Materials and Methods

An in-office whitening agent containing 35% hydrogen peroxide was used. A prefilled tray with a whitening agent containing 6% hydrogen peroxide was used for at-home whitening. Sixty-six subjects were randomly assigned to three groups. Group I: at-home whitening was performed 10 times between the in-office whitening treatments. Group II: at-home whitening was performed five times between the in-office whitening treatments. Group III: only in-office whitening was performed. The tooth color changes were evaluated using a spectrophotometer. A visual analog scale was used to express the pain intensity.

Results

All the groups showed increased ΔE*ab, ΔE00, and ΔWID with increased whitening sessions. Group I at the 3rd whitening session showed significantly higher ΔE*ab, ΔE00, and ΔWID than group III. Tooth sensitivity showed higher values up to 24 h after whitening.

Conclusions

Although dual whitening with the prefilled tray and in-office whitening had higher whitening ability than in-office whitening alone, the intensity and absolute risk of tooth sensitivity was similar.

Clinical Relevance

The dual whitening might produce faster and stronger whitening effects than in-office whitening alone.

DATA AVAILABILITY STATEMENT

The data that support the findings of this study are available on request from the corresponding author upon reasonable request.

The full text of this article hosted at iucr.org is unavailable due to technical difficulties.