The association between periodontitis and sleep duration
Corresponding Author
Mario Romandini
School of Dentistry, Catholic University of the Sacred Heart, Rome, Italy
Department of Periodontology, Catholic University of the Sacred Heart, Rome, Italy
Department of Periodontology and Prosthodontics, “G. Eastman” Dental Hospital, Rome, Italy
Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy
Address:
Mario Romandini
Giovanni XXIII Square 24
74123 Taranto
Italy
E-mail: [email protected]
Search for more papers by this authorGioele Gioco
School of Dentistry, Catholic University of the Sacred Heart, Rome, Italy
Search for more papers by this authorGiorgio Perfetti
Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy
Search for more papers by this authorGiorgio Deli
School of Dentistry, Catholic University of the Sacred Heart, Rome, Italy
Department of Periodontology, Catholic University of the Sacred Heart, Rome, Italy
Search for more papers by this authorEdoardo Staderini
School of Dentistry, Catholic University of the Sacred Heart, Rome, Italy
Search for more papers by this authorAndreina Laforì
School of Dentistry, Catholic University of the Sacred Heart, Rome, Italy
Department of Periodontology, Catholic University of the Sacred Heart, Rome, Italy
Search for more papers by this authorCorresponding Author
Mario Romandini
School of Dentistry, Catholic University of the Sacred Heart, Rome, Italy
Department of Periodontology, Catholic University of the Sacred Heart, Rome, Italy
Department of Periodontology and Prosthodontics, “G. Eastman” Dental Hospital, Rome, Italy
Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy
Address:
Mario Romandini
Giovanni XXIII Square 24
74123 Taranto
Italy
E-mail: [email protected]
Search for more papers by this authorGioele Gioco
School of Dentistry, Catholic University of the Sacred Heart, Rome, Italy
Search for more papers by this authorGiorgio Perfetti
Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy
Search for more papers by this authorGiorgio Deli
School of Dentistry, Catholic University of the Sacred Heart, Rome, Italy
Department of Periodontology, Catholic University of the Sacred Heart, Rome, Italy
Search for more papers by this authorEdoardo Staderini
School of Dentistry, Catholic University of the Sacred Heart, Rome, Italy
Search for more papers by this authorAndreina Laforì
School of Dentistry, Catholic University of the Sacred Heart, Rome, Italy
Department of Periodontology, Catholic University of the Sacred Heart, Rome, Italy
Search for more papers by this authorAbstract
Aim
Due to its potential to influence systemic inflammation and oxidative stress, and to predispose to bacterial infections, sleep duration could potentially be a risk factor for periodontitis. The aim of this cross-sectional study was to evaluate if there was in 2012 an association between periodontitis and sleep duration in a representative sample of the South Korean population.
Materials and Methods
A total of 5812 subjects representative of 39.4 million of adults were examined. Multivariate logistic regressions were applied controlling for age, gender, education, smoking status, alcoholism and consumption frequency of coffee, tea, chocolate and red wine.
Results
Compared to the group sleeping ≤5 h/day, the adjusted odds ratios for periodontitis prevalence defined as Community Periodontal Index (CPI) = 4 were OR = 2.46 (95% CI: 1.20–5.06) in the 6 h/day sleepers group, OR = 2.66 (95% CI: 1.35–5.25) in the 7 h/day sleepers group, OR = 2.29 (95% CI: 1.13–4.63) in the 8 h/day sleepers group and OR = 4.27 (95% CI: 1.83–9.97) in the ≥9 h/day sleepers group. The association has shown to be highlighted in middle-aged people, females, non-smokers, lower educated, with lower lead and higher cadmium blood levels and with higher carotene dietary intake ones and to be partially mediated by lipid profile alterations, diabetes, serum Vitamin D levels and WBC count.
Conclusions
A novel, direct and independent association between sleep duration and the prevalence of periodontitis was found. However, it needs to be investigated how the factors influencing the sleep duration affect this association.
Supporting Information
| Filename | Description |
|---|---|
| jcpe12713-sup-0001-TableS1.docxWord document, 495.8 KB | Table S1. Missing data. |
| jcpe12713-sup-0002-TableS2.docxWord document, 20.5 KB | Table S2. Confounders selection for CPI ≥ 3 case definition. |
| jcpe12713-sup-0003-TableS3.docxWord document, 20.8 KB | Table S3. Confounders selection for CPI = 4 case definition. |
| jcpe12713-sup-0004-FigS1.jpgimage/jpg, 800.5 KB | Figure S1. Flow diagram for participant selection. |
| jcpe12713-sup-0005-AppendixS1.docxWord document, 112.7 KB | Appendix S1. Covariate assessment methods. |
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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