Assessment of corneal layers thickness with spectral-domain optical coherence tomography
Abstract
Purpose
To assess the corneal layers thickness in healthy young adults using spectral-domain anterior segment optical coherence tomography (AS-OCT).
Methods
There were 86 eyes of 86 healthy volunteers, 55 females and 31 males, which were included in the study. The mean age ± standard deviation (SD) was 22.87 ± 3.90 years (range, 20–43). Spectral-domain AS-OCT was performed using Spectralis OCT (Spectralis; Heidelberg Engineering, Heidelberg, Germany). Measurements of central corneal thickness, and central thickness of epithelium, Bowman's layer, stroma and the complex Descemet-endothelium were performed.
Results
Mean central corneal thickness, epithelium, Bowman, stroma and Descemet-endothelium were 555.50 ± 29.64 µm (range 510–624), 54.60 ± 4.25 µm (range 45–63), 16.70 ± 1.73 µm (range 14–20), 467.51 ± 28.91 µm (range 420–533) and 16.74 ± 1.66 µm (range 14–20), respectively.
Conclusions
Spectralis OCT can be easily used to non-invasive measurements of the anterior segment parameters and this study establishes a normal database for corneal thickness and all its layers in healthy young adults.