Partial thickness Macular holes and pharmaceutical treatment of FTMH

The pathophysiology of full thickness macular hole and lamellar macular hole are different and will be discussed. Oct characteristics will be repeated according to new classification. Taking in account the natural history, indication of treatment will be detailled according to each stage of those diseases. Recently, ocriplasmin has been introduced as an alternative treatment to vitrectomy. Favorable Prognostic factors have been recognized as age inferior to 65 years old, full thickness macular hole < 400 microns, the absence of epiretinal membrane, vitreous adhesion < 1500 microns and phakic status. While management of full thickness macular hole shows good visual prognosis for the patients, the visual result of lamelar macular hole is not so obvious.