Sealed-capsule irrigation with distilled deionized water to prevent posterior capsule opacification
Summary
Purpose
To evaluate efficacy and safety of sealed-capsule irrigation (SCI) using distilled water (DW).
Materials and methods
Phacoemulsification was performed in 60 patients. In the control the capsular bag was mechanically cleaned (MC), in the DW group DW for 3′ in SCI was additionally applied. SN60WF IOL was implanted in all eyes. Examinations were performed before and 1, 30, 180 days, 1 and 2 years after surgery. UDVA, CDVA, IOP, K2-SIA, SEQ, endothelial cell and the complications were examined. Total PCO score in the area of 1, 3 mm and capsulorhexis (CAPS) were determined using EPCO 2000.
Results
As far as safety parameters are concerned, no differences were observed between groups (P > 0.05). However, in the DW group the endothelial cell loss was higher (P < 0.05). Total PCO score differences were observed in both groups between the areas (P < 0.05). In CAPS area both, Total PCO score and PCO area were decreased in DW group (P < 0.05). PCO was also lower within 3 mm zone in the DW group (P < 0.05).
Conclusions
SCI is a safe procedure and the endothelial cells loss can be associated with the Perfect Capsule™ device in the anterior chamber insertion. DW irrigated for 3′ reduces PCO in long-term follow-up.